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  1. 2 days ago · African trypanosomiasis, also known as African sleeping sickness or simply sleeping sickness, is an insect-borne parasitic infection of humans and other animals. [3] It is caused by the species Trypanosoma brucei. [3] Humans are infected by two types, Trypanosoma brucei gambiense (TbG) and Trypanosoma brucei rhodesiense (TbR). [3]

  2. May 16, 2024 · Chagas disease, infection with the flagellate protozoan Trypanosoma cruzi. It is transmitted to humans by bloodsucking reduviid bugs and is endemic in most rural areas of Central and South America. Chagas disease was discovered in 1908–09 by Brazilian physician Carlos Chagas.

    • The Editors of Encyclopaedia Britannica
  3. 4 days ago · Chagas disease is caused by Trypanosoma cruzi, a protozoan parasite that displays considerable genetic diversity. Infections result in a range of pathological outcomes, and different strains can exhibit a wide spectrum of anti-parasitic drug tolerance.

  4. 3 days ago · The first document of human infection by T. cruzi was obtained from mummies of 9,000 years of the Chinchorro civilisation that inhabited the coastal region of Chile and Peru. ( 1) The presence of T. cruzi DNA in other mummies made it possible to estimate a prevalence rate for ChD of 40.6%.

  5. May 10, 2024 · Hermann E, Alonso-Vega C, Berthe A, Truyens C, Flores A, Cordova M, et al. Human congenital infection with Trypanosoma cruzi induces phenotypic and functional modifications of cord blood NK cells.

  6. 4 days ago · key words: Trypanosoma cruzi pharmacokinetics in vitro assays dormancy animal model. American trypanosomiasis, widely known as Chagas disease (CD), is caused by the protozoan parasite Trypanosoma cruzi ( T. cruzi) and considered a neglected tropical disease (NTD) by the World Health Organization. ( 1) It was first described more than 100 years ...

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