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3 days ago · Morphine, a natural opioid found in opium, triggers synaptic plasticity and alters neuronal function in the ventral tegmental area (VTA) and nucleus accumbens (NAc), two key structures of the DA ...
May 13, 2024 · During learning, dopamine neurons in the ventral tegmental area (VTA DA neurons) exhibit a phasic prediction-error signal when something unexpected occurs and we need to learn about it. This...
May 21, 2024 · In the striatum or in the Nucleus Accumbens, dopamine is able to trigger potentiation at corticostriatal synapses on medium spiny neurons (MSNs) that were depolarized 200 ms to 2 seconds before...
May 23, 2024 · To address this issue, we targeted the "reward center" of the brain, the nucleus accumbens (NAc), in which itch-responsive neurons have been found in rodents. We examined how neurons in the NAc are activated or suppressed during histamine-induced scratching behaviors in mice.
May 23, 2024 · Nucleus accumbens (NAc) is a component of the ventral striatum in the basal ganglia and is divided into two subdivisions: shell (NAsh) and core (NAco). 9 The predominant cell population is the medium spiny neurons (MSNs) (more than 95% are GABAergic cells) in the NAc, and they receive dopaminergic afferent from ventral tegmental area (VTA) and ...
May 22, 2024 · We recently showed that MCH suppresses dopamine release in the nucleus accumbens, which principally receives dopaminergic projections from the ventral tegmental area (VTA), but the mechanisms underlying MCH-regulated dopamine release are not clearly defined.
May 28, 2024 · Amylin receptor activation in the ventral tegmental area (VTA), a key dopaminergic nucleus in the mesolimbic reward system, has a potent ability to suppress intake of palatable fat and sugar solutions.
