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5 days ago · DOI: 10.1093/brain/awae173 Abstract Comprehensive understanding of the neural circuits involving the ventral tegmental area is essential for elucidating the anatomo-functional mechanisms governing human behaviour as well as the therapeutic and adverse effects of deep brain stimulation for neuropsychiatric diseases.
May 21, 2024 · Ventral tegmental area dopamine projections to the hippocampus trigger long-term potentiation and contextual learning. Fares J. P. Sayegh, Lionel Mouledous, Catherine Macri, Juliana Pi...
May 13, 2024 · The orbitofrontal cortex and ventral tegmental area are necessary for learning from unexpected outcomes. Neuron 62 , 269–280 (2009). Article CAS PubMed PubMed Central Google Scholar
May 6, 2024 · We reconstructed five tracts connecting ventral tegmental area (VTA) and the dorsolateral prefrontal cortex (dlPFC), ventral lateral PFC (vlPFC), medial orbitofrontal cortex (mOFC), anterior cingulate cortex (ACC) and nucleus accumbens (NAc) within meso-cortical and meso-limbic pathways using diffusion weighted imaging.
May 15, 2024 · Psychosis is a complex disorder characterized by deficits in motivation, learning, and salience detection (e.g. novelty) that can emerge even before clinical onset in populations at clinical high-risk (CHR) for developing psychosis. Animal research shows that hippocampal (HPC) novelty signals lead to increased sustained mesolimbic engagement, which in turn magnifies phasic ventral tegmental ...
4 days ago · Since the clinical introduction of general anesthesia, its underlying mechanisms have not been fully elucidated. The ventral tegmental area (VTA) and parabrachial nucleus (PBN) play pivotal roles in the mechanisms underlying general anesthesia. However, whether dopaminergic (DA) projections from the VTA to the PBN play a role in mediating the effects of general anesthesia is unclear. We ...
3 days ago · Ventral tegmental area: anatomy, functions and disorders. May 31, 2024. The ventral tegmental area is a region of the mesencephalon , also known as the middle brain, which is very important because of its involvement in the reinforcement circuit, responsible for the sensations of pleasure and motivated behavior.
