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  1. Jun 5, 2024 · Malaria can be a severe, potentially fatal disease, especially when caused by Plasmodium falciparum. Ensure prompt diagnosis followed by immediate treatment. The treatment regimen depends on infecting plasmodium species, patient's clinical status, drug-resistance status, and previous use of antimalarials. In the absence of prompt diagnosis and ...

  2. Jun 24, 2024 · FDA has announced a temporary shortage of Mefloquine Hydrochloride, one of the medications used to treat uncomplicated malaria. Clinicians who would like to discuss alternative options for specific populations can contact the CDC malaria hotline/clinical consult service at malaria@cdc.gov, or call Monday–Friday, 9 am–5 pm EST 770-488-7788 ...

  3. Jun 5, 2024 · Background Severe malaria is a life-threatening infection, particularly affecting children under the age of 5 years in Africa. Current treatment with parenteral artemisinin derivatives is highly efficacious. However, artemisinin partial resistance is widespread in Southeast Asia, resulting in delayed parasite clearance after therapy, and has emerged independently in South America, Oceania, and ...

    • Jane Achan
  4. Jun 24, 2024 · Uncomplicated malaria: Symptoms may include fever, chills, sweats, headaches, muscle pains, nausea, and vomiting. Severe malaria: Symptoms may include confusion, coma, focal neurologic signs, severe anemia, respiratory difficulties, and organ dysfunction. Patients with symptoms of severe malaria should be assessed and treated immediately.

  5. Jun 5, 2024 · Target product profile: Severe malaria treatments must be highly potent, with rapid onset of antiparasitic activity to clear the infection as quickly as possible to prevent complications. They should also have a low potential for drug resistance selection, given the high parasite burden in patients with severe malaria.

  6. 5 days ago · Nigeria accounts for 39% of global malaria deaths in children under 5 years of age and the effective management of severe malaria is a health priority. The Annual Nigeria Severe Malaria Stakeholders Workshop, ... Emmanuel Shekarau, Miriam Uzoanya and Nnenna Ogbulafor. Malaria Journal 2024 23 :177.

  7. Jun 21, 2024 · Malaria is a mosquito-borne disease that is caused by Plasmodium parasites. Patients with malaria experience flu-like symptoms and, in severe cases, the disease can progress to neurological ...

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