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  1. May 23, 2024 · Efficacy of Doxycycline as PEP to Prevent Bacterial STIs. Doxycycline Individual Level Harms – Antimicrobial Resistance. Doxycycline Use and Adverse Events.

  2. May 23, 2024 · with men who have sex with men (MSM) and transgender women being disproportionately impacted. In the past 5 years, studies have examined the potential of doxycycline as post-exposure prophylaxis (PEP) for STIs. Doxycycline is a broad-spectrum tetracycline, recommended as treatment for chlamydia and syphilis and is not recommended for gonorrhoea ...

  3. 2 days ago · Results from the ANRS 174 Doxyvac phase 3 clinical trial concluded Doxycycline PEP strongly reduced the incidence of chlamydia and syphilis. These researchers said it did not show the efficacy of the 4CmenB vaccine for gonorrhea. Still, doxycycline PEP should be assessed in other broader populations, and its effect on antimicrobial resistance ...

  4. May 23, 2024 · Doxycycline PEP strongly reduced the incidence of chlamydia and syphilis in MSM, but we did not show efficacy of the 4CmenB vaccine for gonorrhoea. Doxycycline PEP should be assessed in other populations, such as heterosexual men and women, and its effect on antimicrobial resistance carefully monitored.

  5. May 23, 2024 · Doxycycline prophylaxis and meningococcal group B vaccine to prevent bacterial sexually transmitted infections in France (ANRS 174 DOXYVAC): a multicentre, open-label, randomised trial with a 2 × 2 factorial design - The Lancet Infectious Diseases. Articles | Online First.

  6. May 21, 2024 · BPG is the first line treatment for syphilis and the only WHO-recommended treatment for pregnant women with syphilis. As second line treatment, doctors may also use doxycycline, ceftriaxone or azithromycin, which are antibiotic medicines. BPG is also used to treat later stages of syphilis, but more doses are required.

  7. May 21, 2024 · Key facts. More than 1 million curable sexually transmitted infections (STIs) are acquired every day worldwide in people 15–49 years old, the majority of which are asymptomatic. In 2020 there were are an estimated 374 million new infections in people 15–49 years with 1 of 4 curable STIs: chlamydia, gonorrhoea, syphilis and trichomoniasis.

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