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6 days ago · Sepsis, systemic inflammatory condition that occurs as a complication of infection and in severe cases may be associated with acute and life-threatening organ dysfunction. Sepsis is a common cause of illness and mortality in hospitals. Learn more about the causes, symptoms, and treatment of sepsis.
- Kara Rogers
3 days ago · Microbial factors. Bacterial virulence factors, such as glycocalyx and various adhesins, allow colonization, immune evasion, and establishment of disease in the host. Sepsis caused by gram-negative bacteria is thought to be largely due to a response by the host to the lipid A component of lipopolysaccharide, also called endotoxin.
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1 day ago · Compound called lolamicin targets a group of harmful microbes but does not disturb those that live peacefully in the gut. ... and can trigger sepsis, ... Lolamicin had anti-microbial effects ...
5 hours ago · Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection, commonly associated with nosocomial transmission. Gram-negative bacterial species are particularly problematic due to the release of the lipopolysaccharide toxins upon cell death. The lipopolysaccharide toxin of E. coli has a greater immunogenic potential than that of other Gram-negative ...
May 7, 2024 · Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Evidence of organ dysfunction includes clinical and laboratory abnormalities of the respiratory system, coagulation, liver, cardiovascular system, nervous system, and kidneys ( Table 79–1 ).
2 days ago · Diagnosis and treatment of sepsis and septic shock are fundamental for emergency clinicians, and include knowledge of clinical and laboratory indicators of subtle and overt organ dysfunction, infection source control, and protocols for prompt identification of the early signs of septic shock. This issue is a structured review of the literature ...
May 2, 2024 · Diagnosing sepsis remains problematic. Pathogen identification is frequently lacking and the dysregulated host response is non-specific. Blood cultures often take days to deliver a result and, even then, approximately 90% are negative, sometimes despite strong clinical evidence of sepsis. Standard host-response biomarkers such as C-reactive ...
