Search results
The study of abiogenesis aims to determine how pre-life chemical reactions gave rise to life under conditions strikingly different from those on Earth today. It primarily uses tools from biology and chemistry , with more recent approaches attempting a synthesis of many sciences.
- Overview
- The Oparin-Haldane theory
- The Miller-Urey experiment
- Modern conceptions of abiogenesis
- GeneratedCaptionsTabForHeroSec
abiogenesis, the idea that life arose from nonlife more than 3.5 billion years ago on Earth. Abiogenesis proposes that the first life-forms generated were very simple and through a gradual process became increasingly complex. Biogenesis, in which life is derived from the reproduction of other life, was presumably preceded by abiogenesis, which became impossible once Earth’s atmosphere assumed its present composition.
Although many equate abiogenesis with the archaic theory of spontaneous generation, the two ideas are quite different. According to the latter, complex life (e.g., a maggot or mouse) was thought to arise spontaneously and continually from nonliving matter. While the hypothetical process of spontaneous generation was disproved as early as the 17th century and decisively rejected in the 19th century, abiogenesis has been neither proved nor disproved.
In the 1920s British scientist J.B.S. Haldane and Russian biochemist Aleksandr Oparin independently set forth similar ideas concerning the conditions required for the origin of life on Earth. Both believed that organic molecules could be formed from abiogenic materials in the presence of an external energy source (e.g., ultraviolet radiation) and that the primitive atmosphere was reducing (having very low amounts of free oxygen) and contained ammonia and water vapour, among other gases. Both also suspected that the first life-forms appeared in the warm, primitive ocean and were heterotrophic (obtaining preformed nutrients from the compounds in existence on early Earth) rather than autotrophic (generating food and nutrients from sunlight or inorganic materials).
Oparin believed that life developed from coacervates, microscopic spontaneously formed spherical aggregates of lipid molecules that are held together by electrostatic forces and that may have been precursors of cells. Oparin’s work with coacervates confirmed that enzymes fundamental for the biochemical reactions of metabolism functioned more efficiently when contained within membrane-bound spheres than when free in aqueous solutions. Haldane, unfamiliar with Oparin’s coacervates, believed that simple organic molecules formed first and in the presence of ultraviolet light became increasingly complex, ultimately forming cells. Haldane and Oparin’s ideas formed the foundation for much of the research on abiogenesis that took place in later decades.
In 1953 American chemists Harold C. Urey and Stanley Miller tested the Oparin-Haldane theory and successfully produced organic molecules from some of the inorganic components thought to have been present on prebiotic Earth. In what became known as the Miller-Urey experiment, the two scientists combined warm water with a mixture of four gases—water ...
Modern abiogenesis hypotheses are based largely on the same principles as the Oparin-Haldane theory and the Miller-Urey experiment. There are, however, subtle differences between the several models that have been set forth to explain the progression from abiogenic molecule to living organism, and explanations differ as to whether complex organic molecules first became self-replicating entities lacking metabolic functions or first became metabolizing protocells that then developed the ability to self-replicate.
Are you a student? Get Britannica Premium for only 24.95 - a 67% discount!
Learn More
The habitat for abiogenesis has also been debated. While some evidence suggests that life may have originated from nonlife in hydrothermal vents on the ocean floor, it is possible that abiogenesis occurred elsewhere, such as deep below Earth’s surface, where newly arisen protocells could have subsisted on methane or hydrogen, or even on ocean shores, where proteinoids may have emerged from the reaction of amino acids with heat and then entered the water as cell-like protein droplets.
Some scientists have proposed that abiogenesis occurred more than once. In one example of this hypothetical scenario, different types of life arose, each with distinct biochemical architectures reflecting the nature of the abiogenic materials from which they developed. Ultimately, however, phosphate-based life (“standard” life, having a biochemical architecture requiring phosphorus) gained an evolutionary advantage over all non-phosphate-based life (“nonstandard” life) and thereby became the most widely distributed type of life on Earth. This notion led scientists to infer the existence of a shadow biosphere, a life-supporting system consisting of microorganisms of unique or unusual biochemical structure that may have once existed, or possibly still exists, on Earth.
As the Miller-Urey experiment demonstrated, organic molecules can form from abiogenic materials under the constraints of Earth’s prebiotic atmosphere. Since the 1950s, researchers have found that amino acids can spontaneously form peptides (small proteins) and that key intermediates in the synthesis of RNA nucleotides (nitrogen-containing compounds [bases] linked to sugar and phosphate groups) can form from prebiotic starting materials. The latter evidence may support the RNA world hypothesis, the idea that on early Earth there existed an abundance of RNA life produced through prebiotic chemical reactions. In fact, in addition to carrying and translating genetic information, RNA is a catalyst, a molecule that increases the rate of a reaction without itself being consumed, meaning that a single RNA catalyst could have produced multiple living forms, which would have been advantageous during the rise of life on Earth. The RNA world hypothesis is one of the leading self-replication-first conceptions of abiogenesis.
Abiogenesis is the idea that life arose from nonlife on Earth more than 3.5 billion years ago. Learn about the Oparin-Haldane theory, the Miller-Urey experiment, and modern hypotheses of abiogenesis.
- Kara Rogers
Apr 28, 2017 · Learn what abiogenesis is and how it relates to evolution and the origin of life. Find out how experiments and evidence support the theory of abiogenesis and its challenges.
Feb 1, 2023 · The theory of abiogenesis posits that the first lifeforms which arose from the primordial soup were simple organisms that gradually became more complex throughout aeons. Abiogenesis is different ...
- Reginald Davey
Dec 31, 2012 · The realization that abiogenesis—the chemical process by which simplest life emerged from inanimate beginnings—and biological evolution may actually be one single continuous physico-chemical process with an identifiable driving force opens up new avenues towards resolution of the OOL problem [1,7,12,13]. In fact that unification actually ...
- Addy Pross, Robert Pascal
- 10.1098/rsob.120190
- 2013
- Open Biol. 2013 Mar; 3(3): 120190.
Life - Origin, Evolution, Abiogenesis: Perhaps the most fundamental and at the same time the least understood biological problem is the origin of life. It is central to many scientific and philosophical problems and to any consideration of extraterrestrial life. Most of the hypotheses of the origin of life will fall into one of four categories ...
Feb 23, 2022 · It limits consideration to how a loosened vision of life's chemical foundations might usefully progress the science of abiogenesis. This narrower focus finds its deepest and most deliberate alignment with another, singular philosophical contribution that challenged readers to rethink an older debate within origins research, namely the ...
