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Marguerite Alice "Missy" LeHand (September 13, 1896 – July 31, 1944) was a private secretary to U.S. President Franklin D. Roosevelt (FDR) for 21 years. According to LeHand's biographer Kathryn Smith in The Gatekeeper, she eventually functioned as White House Chief of Staff, the only woman in American history to do so. Wikipedia