Search results
Dec 5, 2020 · We did the first randomised clinical trial in the USA of extracorporeal membrane oxygenation (ECMO)-facilitated resuscitation versus standard ACLS treatment in patients with OHCA and refractory ventricular fibrillation.
- Demetris Yannopoulos, Jason Bartos, Ganesh Raveendran, Emily Walser, John Connett, Thomas A Murray, ...
- 2020
Nov 13, 2020 · To our knowledge, the ARREST trial is the first randomised interventional trial to assess the effect of early ECMO-facilitated resuscitation compared with standard ACLS treatment for survival of patients with out-of-hospital refractory cardiac arrest.
- Demetris Yannopoulos, Jason Bartos, Ganesh Raveendran, Emily Walser, John Connett, Thomas A Murray, ...
- 2020
Aug 27, 2023 · ARREST is the first and only randomised trial of delivery to a cardiac arrest centre following resuscitated OHCA in the community. The success of this trial is attributable to the research infrastructure at the London Ambulance Service and the pan-London cardiac network, which facilitated the success of a trial of this scale and complexity.
Nov 13, 2020 · Yannopoulos D, Bartos J, Raveendran G, et al. Advanced reperfusion strategies for patients with out-of-hospital cardiac arrest and refractory ventricular fibrillation (ARREST): a phase 2, single centre, open-label, randomized controlled trial.
Jan 25, 2023 · A previous randomized, controlled trial that compared extracorporeal CPR with conventional CPR in out-of-hospital cardiac arrest owing to ventricular arrhythmias was the ARREST (Advanced ...
Jul 3, 2021 · The ARREST trial was a phase 2, single-centre, open-label, adaptive, safety and efficacy randomised clinical trial comparing early extracorporeal membrane oxygenation (ECMO)-facilitated resuscitation to standard advanced cardiac life support (ACLS) in adults with out-of-hospital refractory ventricular fibrillation cardiac arrest.
Feb 22, 2022 · The ARREST trial showed that ECMO-facilitated resuscitation for patients with OHCA and refractory ventricular fibrillation significantly improved survival to hospital discharge and functional status compared with patients receiving standard advanced cardiac life support (6/14 patients [43%] vs 1/15 [7%]; risk difference, 36.2% [95% CI, 3.7% to ...