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  1. General guidelines for the treatment of women with von Willebrand disease at delivery. Since pregnant women with VWD are at increased risk of postpartum hemorrhage if untreated 9, 17, 27, 31, treatment options should be planned at the beginning of pregnancy.

    • Table 1

      Given the wide heterogeneity of phenotypes and of the...

    • Mcmdm-1Vwd

      Introduction. von Willebrand factor (VWF) is a multimeric...

  2. May 20, 2019 · The variable pattern of changes observed during pregnancy of von Willebrand factor (VWF) and factor VIII (FVIII), the protein carried by VWF, prompts a careful evaluation of pregnant women with VWD to plan the most appropriate treatment at the time of parturition.

    • Giancarlo Castaman, Paula D. James
    • 2019
  3. In the pregnant patient, Von Willebrand disease poses an increased risk of complications during labor or the postpartum period, attributed to a higher likelihood of experiencing postpartum hemorrhage and its consequential complications arising from transfusion support and multiorgan injury due to tissue hypoperfusion.

  4. Feb 14, 2024 · Key points. With proper care, women with von Willebrand disease (VWD) can have a successful pregnancy and deliver a healthy child. Close monitoring throughout pregnancy is important for women with VWD. Women with VWD are at risk for serious bleeding after delivery. Pregnancy and childbirth.

  5. Nov 5, 2020 · Carriers of hemophilia A (HA) or hemophilia B (HB) and women suffering from von Willebrand disease (VWD) have an increased risk for bleeding during pregnancy and delivery. Management of these women concerns not only managing the bleeding tendency of the mother, but also that of the child with a potential bleeding disorder.

    • Frank W G Leebeek, Johannes Duvekot, Marieke J H A Kruip
    • 2020
  6. Jun 7, 2022 · Although VWD occurs equally in males and females, women are at a higher risk of being affected, mostly because of bleeding challenges associated with menstruation, pregnancy, and childbirth [ 1, 7, 8 ]. During pregnancy, many changes in hemostasis occur that result in a hypercoagulable state.

  7. Apr 26, 2010 · hemorrhage. pregnancy. von Willebrand disease. A 26-year-old patient was seen for routine prenatal care. She had a history of delayed postpartum hemorrhage 4 years earlier after an uncomplicated vaginal delivery. During a recent visit to the dentist, she experienced increased bleeding after a tooth extraction.

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  2. See official information about a von Willebrand disease treatment for adults.

  3. Learn More About Treating Hemophilia A. Find Resources to Educate Patients on Factor Activity & Hemophilia A Management.

  4. Visit the official HCP website for a FDA-approved treatment for myelofibrosis. See Important Safety Information and full Prescribing Information, sign up to learn more.

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