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Huntington's disease causes nerve cells in the brain to decay over time. The disease affects a person's movements, thinking ability and mental health.
Huntington's disease is rare. It's often passed down through a changed gene from a parent.
Huntington's disease symptoms can develop at any time, but they often begin when people are in their 30s or 40s. If the disease develops before age 20, it's called juvenile Huntington's disease. When Huntington's develops early, symptoms c...
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Huntington's disease usually causes movement disorders. It also causes mental health conditions and trouble with thinking and planning. These conditions can cause a wide spectrum of symptoms. The first symptoms vary greatly from person to person. Some symptoms appear to be worse or have a greater effect on functional ability. These symptoms may change in severity throughout the course of the disease.
The movement disorders related to Huntington's disease may ...
Huntington's disease is caused by a difference in a single gene that's passed down from a parent. Huntington's disease follows an autosomal dominant inheritance pattern. This means that a person needs only one copy of the nontypical gene to develop the disorder.
With the exception of genes on the sex chromosomes, a person inherits two copies of every gene — one copy from each parent. A parent with a nontypical gene could pass along the nontypical copy of the gene or the healthy copy. Each ch...
No treatments can alter the course of Huntington's disease. But medicines can lessen some symptoms of movement and mental health conditions. And multiple interventions can help a person adapt to changes in abilities for a certain amount of time.
The medicines you take may change over the course of the disease, depending on your overall treatment goals. Also, medicines that treat some symptoms may result in side effects that worsen other symptoms. Treatment goals are regularly revi...
People with a known family history of Huntington's disease may be concerned about whether they may pass the Huntington gene on to their children. They might consider genetic testing and family planning options.
If an at-risk parent is considering genetic testing, it can be helpful to meet with a genetic counselor. A genetic counselor explains the potential risks of a positive test result, which may mean that the parent may develop the disease. Also, couples may need to make additional choices about whethe...
For informational purposes only and not a substitute for professional medical advice, diagnosis, or treatment.
© Mayo Clinic
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