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Malignant hyperthermia is a severe reaction to certain drugs used for anesthesia. This severe reaction typically includes a dangerously high body temperature, rigid muscles or spasms, a rapid heart rate, and other symptoms. Without prompt treatment, the complications caused by malignant hyperthermia can be fatal.
In most cases, the gene that puts you at risk of malignant hyperthermia is inherited, though sometimes it's the result of a random genetic change. Genetic testing can reveal wheth...
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In most cases, no signs or symptoms of susceptibility to malignant hyperthermia exist until you're exposed to certain drugs used for anesthesia.
Signs and symptoms of malignant hyperthermia may vary and can occur during anesthesia or during recovery shortly after surgery. They can include:
In rare cases, people at risk of malignant hyperthermia have shown signs of a reaction after intense physical activity during excessive heat or humidity, during a viral illness, o...
Malignant hyperthermia can result when you have MHS, a genetic disorder that's caused by a gene change (mutation). The affected gene increases your risk of malignant hyperthermia when you're exposed to certain anesthesia drugs that trigger a reaction. The affected gene is most commonly inherited, usually from one parent who also has it. Less often, the affected gene is not inherited and is the result of a random gene change.
Different genes can cause MHS. The most commonly affected g...
If you or someone in your family has MHS or you think you may be at risk of malignant hyperthermia, it's important to tell your health care provider and anesthesiologist before you get anesthesia. Drugs that do not trigger malignant hyperthermia may be used as part of your anesthesia.
Immediate treatment of malignant hyperthermia includes:
With treatment, malignant hyperthermia usually resolves within a few days. Follow-up care If you've experienced malignant hyperthermia due to certain anesthesia drugs, exercising...
If you have a family history of malignant hyperthermia or a relative who has problems with anesthesia, tell your health care provider or anesthesiologist before surgery or any procedure that requires anesthesia.
Evaluating your risk of malignant hyperthermia allows your anesthesiologist to avoid certain anesthesia drugs.
For informational purposes only and not a substitute for professional medical advice, diagnosis, or treatment.
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