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Temporal summation. Temporal summation is the addition of quickly occurring stimuli at a single synapse that is active repeatedly. A common EPSP lasts about 20 ms. Even so, with maximum stimulation, action potentials can reach axon terminals every millisecond.
The more closely postsynaptic potentials are spaced in time, the larger the eventual sum when they are added together. This concept is called temporal summation. Many small EPSPs all arriving at a decision point at the same time will be likely to result in a superthreshold stimulus.
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What is temporal summation?
What is the difference between temporal and spatial summation?
How does temporal summation affect action potential initiation?
Is temporal summation possible if presynaptic action potentials are close to each other?
Temporal summation is when the stimulus is applied repeatedly in rapid succession. For example, 1 stimulus raises the charge from -60 mV to -58 mV, then another quickly comes in and raises it from -58 mV to -56 mV and so on until, lets say, threshold is reached at -40 mV and an action potential is fired.
- Is the trigger zone the same as the axon hillock?yes.. the trigger zone is located at the axon hillock of the neuron
- I was taught that the resting membrane potential was -70 mV for most cells, not -60 mV. Can you plea...Yes, the avg. resting potential is -70mV, although estimates vary. Just stick with -70. -60 is just another estimate, and as many estimates coverin...
- So do synapses occur at the cell soma too (8:40)? I thought they could only happen at the dendritesYes, synapses occur on the soma. Those are mostly inhibitory. Dendrites are the _primary_ signal reception area, not the _only_ signal reception area.
- Are graded potentials the same thing as electrotonic potentials?Electrotonic potential is a graded response, it does decay with distance and time. So yes.
- Where would the cytoplasm, nucleus, and all the other organelles be in this diagram?Like other cells, the cytoplasm is continuous within all parts of the neuron. The nucleus and most organelles are localized within the cell body......
- So, is the point of graded potentials just to determine whether or not we will have an action potent...Yes. The 'average' neuron has 1000 neurons that synapse on it and tell it what to do by creating graded potentials. Some are excitatory ( depolariz...
- why are two added depolarizations longer, and not only stronger, than one?Since action potentials are achieved by reaching a threshold, there is no way to reach a stronger action potential just from having a "stronger" de...
- Is this really what a neuron looks like or is it simply a model used for explanatory purposes?http://upload.wikimedia.org/wikipedia/commons/f/fb/Gyrus_Dentatus_40x.jpg http://upload.wikimedia.org/wikipedia/commons/3/32/Smi32neuron.jpg some r...
- If two hyperpolarizations happened at the same time, would that lead to a depolarizations, because t...No. Math is different than health and medicine. This will further hyperpolorize the neuron for a short time.
Temporal summation is the relationship of multiple action potentials from a single cell resulting in a significant change in the membrane potential. Spatial and temporal summation can act together, as well.
Apr 25, 2024 · While multiple inputs on a neuron can be summed up easily, temporal summation requires inputs to be closely spaced in time to prevent decay. Inputs from a single source can summate temporally. Closer proximity allows for greater summation, increasing the likelihood of eliciting an action potential.
The integration of postsynaptic potentials that occur in the same place—but at slightly different times—is called temporal summation. For instance, let’s suppose that excitatory synapses are made on two different dendrites of the same postsynaptic neuron, as shown below.
Temporal integration or temporal summation refers to the well-known decrease in detection and discrimination thresholds with increases in the duration of the signal. Most models of this phenomenon (e.g. Plomp and Bouman,1959; Zwislocki, 1960) incorporate “leaky” integration with relatively long time constants, typically hundreds of milliseconds.
