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- The T-even phages, T2, T4, and T6, were used as model systems for the study of virus multiplication. In 1952 Alfred Day Hershey and Martha Chase used the T2 bacteriophage in a famous experiment in which they demonstrated that only the nucleic acids of phage molecules were required for their replication within bacteria.
www.britannica.com › science › bacteriophageBacteriophage | Definition, Life Cycle, & Research | Britannica
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Are bacteriophages appropriate model organisms for Virus emergence research?
Are bacteriophages a good model system?
Which bacteriophage was used to study virus multiplication?
Structural model at atomic resolution of bacteriophage T4 The structure of a typical myovirus bacteriophage Anatomy and infection cycle of bacteriophage T4. A bacteriophage ( / b æ k ˈ t ɪər i oʊ f eɪ dʒ / ), also known informally as a phage ( / ˈ f eɪ dʒ / ), is a virus that infects and replicates within bacteria and archaea .
Sep 16, 2009 · Here, I highlight studies that show that bacteriophages are appropriate model organisms for virus emergence research because of the ease in which important population parameters can be manipulated. Ideally this research will permit identifying major factors determining the persistence or extinction of emerging viruses.
- John J. Dennehy
- 10.1016/j.tim.2009.07.006
- 2009
- Trends Microbiol. 2009 Oct; 17(10): 450-457.
A bacteriophage, or phage for short, is a virus that infects bacteria. Like other types of viruses, bacteriophages vary a lot in their shape and genetic material. Phage genomes can consist of either DNA or RNA, and can contain as few as four genes or as many as several hundred 1, 2, 3. .
- If it's true that 8 percent of our genome were from viruses that merged with our eukaryotic ancestor...That also made me think about mitochondrial diseases. There's this endosymbiotic theory where they said mitochondria and chloroplast were descendan...
- When a phage injects its double stranded DNA to a host does it still remain a phage or does it still...Viruses usually inject their all genetic material into one cell, which helps to spread disease through is assembly and release of new viruses from...
- i thought the antibiotic killing bacteria and viruses. but why the antibiotic kill only viruses? (th...Antibiotics only work on bacteria not viruses. Antibiotics work on specific processes in the life cycle of the bacteria that either kill the bacter...
- what about the classification of bacteriophage? ..how is it classified and what are the differences ...Bacteriophage is in essence, just another virus. It got it's name from the fact that people discovered it infects bacteria (I presume, could be wro...
- what potential dangers could phages even have? Will it accidentally evolve and target human cells?Eukaryotic cells (including humans) are very different from those of Bacteria, so it is very unlikely that a bacteriophage could evolve to target a...
Sep 8, 2020 · Bacteriophages (hence termed phages) are viruses that target bacteria and have long been considered as potential future treatments against antibiotic-resistant bacterial infection. However, the...
- Sara Federici, Samuel P Nobs, Eran Elinav
- 2021
Apr 4, 2024 · Bacteriophage, any of a group of viruses that infect bacteria. Bacteriophages were discovered independently by Frederick W. Twort in Great Britain (1915) and Felix d’Herelle in France (1917). Thousands of varieties of phages exist. Certain types serve key roles in laboratory research.
- The Editors of Encyclopaedia Britannica
Jun 16, 2018 · We suggest a bacteriophage concept of human diseases consisting of the following features: Direct interaction of phages with the host macroorganism (eukaryotic cells and proteins); Indirect interaction with the host macroorganism by causing harmful microbiota alterations and microbiota-related diseases ( Figure 1 ).
Bacteriophage T4 is a model virus, well studied genetically and biochemically, but its structure determination has been challenging because of its large size and unusually prolate-shaped, ∼1,200-Å-long and ∼860-Å-wide capsid.
