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  2. Dr. McKay conducts basic research towards understanding retinal degenerations and the molecular origins of glaucoma, asking the key questions necessary for successful development of cell based therapies. His collaborations with the vitreoretinal surgical staff are central to the projects success.

    • Education

      The University of Arizona has a four-year integrated...

    • McKay Lab

      Brian S. McKay, PhD. Professor. Department of Ophthalmology....

    • The Mckay Laboratory
    • The Mckay Laboratory Team
    • Pigmentation and Vision
    • Age-Related Macular Degeneration
    • Glaucoma

    Brian S. McKay, PhD Professor Department of Ophthalmology and Vision Science Brian McKay was born and educated in Wisconsin. Dr. McKay obtained his BS in Biology from the University of Wisconsin–Milwaukee and his PhD in cell biology and anatomy from the Medical College of Wisconsin in 1995. Postdoctoral training in protein chemistry was obtained at...

    Brian S. McKay, PhD, Principal Investigator BSMcKay@eyes.arizona.edu Nicole Congrove, Senior Laboratory Technologist NCongrove@email.arizona.edu

    The two most common causes of irreversible blindness are Age-related Macular Degeneration (AMD) and glaucoma. The incidence or risk of both diseases is linked to race and pigmentation, but in opposite ways. Those with darker pigmentation appear protected from AMD, but are at significantly greater risk of glaucoma.

    McKay BS, Schwartz SG. Pigmentation and Macular Degeneration: Is There a Role for GPR143? J Ocul Pharmacol Ther. 32: 3–4. doi:10.1089/jop.2016.29007.bsm The McKay Lab specifically investigated one of the pigmentation genes what was a potential orphan G-protein coupled receptor (GPCR). We discovered that the ligand for this receptor (GPR143) is L-DO...

    Locke CJ, Congrove NR, Dismuke WM, Bowen TJ, Stamer WD, McKay BS. Controlled exosome release from the retinal pigment epithelium in situ. Exp Eye Res. The first gene linked to genetic primary open angle glaucoma, POAG, the most common form of the disease, was myocilin. The myocilin gene and protein are expressed throughout the body, but mutations o...

  3. Brian S Mckay | UA Profiles. Professor, Ophthalmology - (Research Scholar Track) Professor, Physiology. Contact. (520) 626-1536. Medical Research Building, Rm. 212. Tucson, AZ 85724. bsmckay@eyes.arizona.edu. Bio. Interests. Courses. Scholarly Contributions. Biography. Chronology of Education: College.

  4. Professor, Physiology. MRB 212. (520) 626-1536. bsmckay@eyes.arizona.edu.

  5. Brian Mckay. Professor, Ophthalmology - (Research Scholar Track) Professor, Physiology

  6. CURRICULUM VITAE. Brian S. McKay, Ph.D. Chronology of Education: College University of Wisconsin, Milwaukee, WI. 1982-1987. B.S. Graduate School Medical College of Wisconsin, Milwaukee, WI. 1989-1995. Ph.D. Postdoctoral training The Scripps Research Institute. 1995-1997.

  7. Dec 13, 2013 · Professor. The University of Arizona. Oct 2002 - Present 21 years 6 months. Tucson, Arizona, United States. I manage a research laboratory investigating a new pathway for treatment of...

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