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  1. Dec 26, 2023 · Harpoon is a biotech company developing novel biologics for cancer and other diseases using a proprietary antibody-based platform called TriTAC. TriTAC unleashes the target cell-killing properties of a patient’s own immune system by engaging T cells.

  2. Jan 8, 2024 · Merck and Harpoon Therapeutics announce a definitive agreement under which Merck will acquire Harpoon for $680 million. Harpoon has a portfolio of novel T-cell engagers, including HPN328, a DLL3 targeting candidate for small cell lung cancer and neuroendocrine tumors.

  3. Mar 11, 2024 · Harpoon’s lead candidate, MK-6070 (formerly known as HPN328), is a T-cell engager targeting delta-like ligand 3 (DLL3), an inhibitory canonical Notch ligand that is expressed at high levels in small cell lung cancer (SCLC) and neuroendocrine tumors.

  4. Mar 11, 2024 · Merck completes the acquisition of Harpoon, a biotech company developing T-cell engagers for cancer treatment. Harpoon's lead candidate, MK-6070, targets DLL3 in small cell lung cancer and neuroendocrine tumors.

  5. Oct 23, 2023 · Harpoon Therapeutics develops T cell engagers to treat cancer and other diseases using its TriTAC, ProTriTAC and TriTAC-XR platforms. See its stock price, company profile and investor relations information.

  6. Mar 11, 2024 · MSD (Merck & Co., Inc., Rahway, N.J., USA) completes the acquisition of Harpoon Therapeutics, a biopharmaceutical company developing novel T-cell engagers for cancer. Harpoon's lead candidate, MK-6070, is a DLL3 targeting T-cell engager for small cell lung cancer and neuroendocrine tumors.

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  8. Jan 8, 2024 · Dive Brief: Merck & Co. is beefing up its cancer pipeline, announcing Monday it will pay $680 million to buy Harpoon Therapeutics for its armory of dual-acting immunotherapies targeting lung, abdominal and blood cancers. Merck agreed to pay $23 per Harpoon share, a 118% premium to the company’s $10.55 closing price Friday.

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