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  1. Jan 31, 2022 · CNN — The first participants have been vaccinated in a Phase 1 clinical trial of an experimental HIV vaccine that utilizes Modernas mRNA technology, the company announced last week. The...

  2. Jun 8, 2023 · Posted on June 6th, 2023 by Lawrence Tabak, D.D.S., Ph.D. Researchers used a customized nanoparticle (top left) to learn more about guiding the immune system to mount a desired robust response, the type needed for an effective HIV vaccine. Credit: Donny Bliss, NIH.

  3. Mar 14, 2022 · The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has launched a Phase 1 clinical trial evaluating three experimental HIV vaccines based on a messenger RNA (mRNA) platform—a technology used in several approved COVID-19 vaccines.

  4. Feb 20, 2023 · In March 2022, the HIV Vaccine Trials Network (HVTN) launched HVTN 302, a study that’s testing three experimental mRNA HIV vaccines designed and developed with support from NIAID. Each of the 108 study volunteers was vaccinated with one of the three experimental vaccines, given at varying doses and followed by booster doses.

  5. Jun 6, 2023 · While this vaccine alone will not offer HIV protection and is intended to be part of an eventual broader, multistep vaccination regimen, the researchers also determined that it elicited a robust immune response in nearly all 36 healthy adult volunteers.

  6. Jan 27, 2022 · The Phase 1 trial, IAVI G002, is designed to test the hypothesis that sequential administration of priming and boosting HIV immunogens delivered by messenger RNA (mRNA) can induce specific classes of B-cell responses and guide their early maturation toward broadly neutralizing antibody (bnAb) development.

  7. Jan 27, 2022 · Moderna announced Thursday that it's launched early-stage clinical trials of an HIV mRNA vaccine. The biotechnology company has teamed up with the nonprofit International AIDS Vaccine Initiative to develop the shot, which uses the same technology as Moderna's successful COVID-19 vaccine.

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