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Jul 24, 2018 · There are multiple levels of CNS involved in the transmission of pain. These include the spinal cord (supraspinal), the brainstem (midbrain, medulla oblongata and the pons), and the cortical regions (cerebral cortex), as shown in Figure 1.
- PMC Free Article
We describe the organization of several ascending...
- The Anatomy and Physiology
Diagrammatic outline of the major neural structures relevant...
- PMC Free Article
Sep 10, 2023 · The classification of pain is complicated and there are many different types of pain, each arsing through unique mechanisms. Types of pain include: sharp pain, prickling pain, thermal pain, aching pain. In addition, the origin of pain can be somatic, visceral, thalamic, neuropathic, psychosomatic, referred or illusionary.
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Figure 1 Ascending pain pathways. DRG dorsal root ganglion, PAG periaqueductal grey matter Pain processing in the brain The experience of pain is complex and subjective, and is affected by factors such as cognition (eg distraction or catastrophising), mood, beliefs and genetics.
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Aug 1, 2014 · The pain pathways form a complex, dynamic, sensory, cognitive, and behavioral system that evolved to detect, integrate, and coordinate a protective response to incoming noxious stimuli that threatens tissue injury or organism survival. 1.
Nov 1, 2021 · Pain can be anatomically and phenomenologically dissected into three separable but interacting pathways, a lateral ‘painfulness’ pathway, a medial ‘suffering’ pathway and a descending pain inhibitory pathway. •. In chronic pain the descending pain inhibitory pathway is less activated. •.