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  2. Jul 24, 2018 · There are multiple levels of CNS involved in the transmission of pain. These include the spinal cord (supraspinal), the brainstem (midbrain, medulla oblongata and the pons), and the cortical regions (cerebral cortex), as shown in Figure 1.

  3. Nov 1, 2021 · Pain can be anatomically and phenomenologically dissected into three separable but interacting pathways, a lateral ‘painfulness’ pathway, a medial ‘suffering’ pathway and a descending pain inhibitory pathway.

    • Dirk De Ridder, Divya Adhia, Sven Vanneste
    • 2021
  4. Nov 10, 2021 · MANIPULATING THE BRAINS AFFECTIVE PATHWAYS TO PROVIDE PAIN RELIEF (FIG. 3B) CONCLUSION. Acknowledgments. REFERENCES AND NOTES. Abstract. Pain is a multidimensional experience with sensory-discriminative, affective-motivational, and cognitive-evaluative components.

    • Nicole Mercer Lindsay, Nicole Mercer Lindsay, Chong Chen, Gadi Gilam, Sean Mackey, Grégory Scherrer
    • 2021
  5. Mar 13, 2019 · Results Pain pathways represent a complex sensory system with cognitive, emotional, and behavioral influences. Anatomically, the hippocampus, amygdala, and anterior cortex—central to the encoding and consolidation of memory—are also implicated in experiential aspects of pain.

  6. Pathophysiology of Pain. Objective. To review the pain pathways in the central and peripheral nervous system and the actions of drugs used to treat pain. Design. An overview of pain pathways is presented, beginning in the periphery and progressing centrally, and the ascending and descending pathways are described in detail. Results.

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