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  1. Apr 15, 2012 · The most common cause is trauma, which often leads to distal nail bed splinter hemorrhages. Systemic causes include endocarditis; psoriasis; renal, pulmonary, and endocrine disease; and...

    • Skin Conditions
    • Vasculitis and Systemic Diseases
    • Infectious Diseases
    • Drug Reactions
    • Other Causes

    Splinter hemorrhages are commonly seen in conditions such as nail psoriasis and lichen planus. Nail psoriasis is an autoimmune disorder that causes skin cells to collect on your nails. Lichen planus is an inflammatory skin condition that often results in an itchy rash. Up to 35% of people with lichen planus reported having splinter hemorrhages.

    Splinter hemorrhages may be due to inflammation of your blood vessels (vasculitis). Several diseases such as antiphospholipid syndrome and lupuscan cause vasculitis.

    Bacterial infections such as endocarditis may cause splinter hemorrhages. Endocarditis is an infection of your heart valves. Studies show that 15% to 33% of people with endocarditis have splinter hemorrhages. People with chronic kidney disease also report them. This may be due to hemodialysisor a kidney transplant.

    Splinter hemorrhages are found in 60% to 70% of people taking kinase inhibitors such as sunitinib and sorafenib. Kinase inhibitors are cancer medications that stop cancer cells from growing. Splinter hemorrhages are also more common in people taking blood thinners such as aspirin, warfarin, apixaban or rivaroxaban.

    There are various other causes of splinter hemorrhages. They can occur because of a rare benign (noncancerous) tumor of your nail called onychomatricoma. They can look similar to a type of skin cancer called subungual melanoma.

  2. Splinter hemorrhages are lesions caused by linear bleeding under a fingernail or toenail, resembling a splinter. Causes. trauma e.g. manual laborers; endocarditis vasculitis (e.g. rheumatoid arthritis, PAN) sepsis; hematological malignancy; profound anemia

  3. A splinter haemorrhage is a longitudinal, red-brown haemorrhage under a nail and looks like a wood splinter. Seen end-on, the haemorrhage is in the lower part of the nail plate or underneath it.

  4. Mar 15, 2004 · Splinter hemorrhage in patients with heart murmur and unexplained fever can herald endocarditis. Patients with telangiectasia, koilonychia, or pitting of the nails may have connective tissue...

  5. Jul 29, 2021 · Clinicians should consider a broad differential diagnosis including antiphospholipid syndrome, vasculitis, drug reactions, infective endocarditis, and renal failure as potential causes of splinter hemorrhages ( 1 ).

  6. Splinter hemorrhage; Splinter hemorrhage on a fingernail of the little finger: Differential diagnosis: subacute infective endocarditis, scleroderma, trichinosis, systemic lupus erythematosus (SLE), rheumatoid arthritis, psoriatic nails, antiphospholipid syndrome

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