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The ventral tegmental area (VTA) (tegmentum is Latin for covering), also known as the ventral tegmental area of Tsai, or simply ventral tegmentum, is a group of neurons located close to the midline on the floor of the midbrain.
Jan 5, 2017 · Dopamine-releasing neurons of the ventral tegmental area (VTA) have central roles in reward-related and goal-directed behaviours. VTA dopamine-releasing neurons are heterogeneous in their...
- Marisela Morales, Elyssa B. Margolis
- 2017
May 20, 2022 · The ventral tegmental area (VTA) is well known for regulating reward consumption, learning, memory, and addiction behaviors through mediating dopamine (DA) release in downstream regions. Other than DA neurons, the VTA is known to be heterogeneous and contains other types of neurons, including glutamate neurons.
- Jing Cai, Qingchun Tong
- Front Neural Circuits. 2022; 16: 867053.
- 10.3389/fncir.2022.867053
- 2022
Dec 5, 2019 · VTA GABA neurons are inhibitory cells that regulate dopaminergic activity and have diverse functions in reward, aversion, and learning. This review article summarizes the circuit architecture, synaptic inputs, and behavioral roles of VTA GABA neurons and their modulation by drugs and stress.
- Chloé Bouarab, Brittney Thompson, Abigail M. Polter
- 2019
Jun 15, 2020 · The ventral tegmental area (VTA) is important for reward processing and motivation. The anatomic organization of neurotransmitter-specific inputs to the VTA remains poorly resolved. In the...
- Marta E. Soden, Amanda S. Chung, Beatriz Cuevas, Jesse M. Resnick, Rajeshwar Awatramani, Larry S. Zw...
- 2020
Oct 14, 2012 · Ventral tegmental area (VTA) dopamine neurons have important roles in adaptive and pathological brain functions related to reward and motivation.
The ventral tegmental area (VTA) is a midbrain region that regulates diverse behaviors through dopamine (DA) and glutamate signaling. This review summarizes the features and functions of VTA glutamate neurons, their connections with other VTA neurons and brain regions, and their roles in reward, aversion, stress, and addiction.
