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1. www.mayoclinic.org › diseases-conditions › pagetsPaget's disease of bone - Symptoms & causes - Mayo Clinic

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   Jan 11, 2023 · Paget's (PAJ-its) disease of bone interferes with your body's normal recycling process, in which new bone tissue gradually replaces old bone tissue. Over time, bones can become fragile and misshapen. The pelvis, skull, spine and legs are most commonly affected.

2. en.wikipedia.org › wiki › Paget&Paget's disease of bone - Wikipedia

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   Paget's disease of bone (commonly known as Paget's disease or, historically, osteitis deformans) is a condition involving cellular remodeling and deformity of one or more bones.

3. my.clevelandclinic.org › health › diseasesPaget's Disease of the Bone: Symptoms, Causes & Treatment

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   Oct 12, 2021 · Paget’s disease of the bone is a rare chronic bone disorder in which there's excessive and disordered bone turnover with both excessive resorption and formation. This is the process by your body breaks down old bone and creates new bone.

4. orthoinfo.aaos.org › pagets-disease-of-bonePaget's Disease of Bone - Symptoms and Treatment - OrthoInfo

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   Paget's disease of bone is a chronic disease of the skeleton. In healthy bone, a process called remodeling removes old pieces of bone and replaces them with new bone. Paget’s disease causes this process to shift out of balance, resulting in new bone that is weak and brittle.

5. www.niams.nih.gov › health-topics › pagets-disease-bonePaget's Disease of Bone - Symptoms & Causes| NIAMS

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   Jul 27, 2023 · Paget’s disease of bone is a chronic (long-lasting) disorder that causes bones to grow larger and become weaker than normal. The disease usually affects just one or a few bones. The bones most commonly affected by Paget’s disease include: Pelvis. Skull. Spine. Femur and tibia (leg bones).

6. www.hopkinsmedicine.org › health › conditions-andPaget Disease of the Bone | Johns Hopkins Medicine

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   Pain. Risk for bone fractures. Very rarely, Paget disease may progress to bone cancer. The symptoms of Paget disease of the bone may look like other bone disorders or medical problems. Always talk with your healthcare provider for a diagnosis. How is Paget disease of the bone diagnosed?