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•Absorbed dose: D = dE/dm, where – dE is the mean energy imparted by ionizing radiation into a volume whose mass is dm – units: MeV/g, erg/g, J/kg, rad, Gy •Dose equivalent: H = D x Q, where – Q is a measure of the relative biological risk caused by a particular type of radiation – Q is end-point specific
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Absorbed dose is a dose quantity which is the measure of the energy deposited in matter by ionizing radiation per unit mass. Absorbed dose is used in the calculation of dose uptake in living tissue in both radiation protection (reduction of harmful effects), and radiology (potential beneficial effects, for example in cancer treatment).
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Aug 5, 2021 · Abstract. This paper presents standardized methods for performing dose calculations for radiopharmaceuticals. Various steps in the process are outlined, with some specific examples given. Special models for calculating time–activity integrals (urinary bladder, intestines) are also reviewed.
- 10.2967/jnumed.121.262034
- 2022/03
- J Nucl Med. 2022 Mar; 63(3): 485-492.
Aug 5, 2021 · Basic dose calculations A ‘generic’ equation for the absorbed dose rate in an organ or tumor in which radioactivity is uniformly distributed is given by: Ḋ = 𝑘 ∑ 𝐴 ∑𝑖 𝑖 𝐸𝑖 𝑖( ) (3) where x D T = absorbed dose rate in the target region T(rad/hr or Gy/sec) A S = activity ( Ci or MBq) in source region S n i
- Michael G Stabin, Richard E. Wendt, Glenn D Flux
- 2021
Dec 14, 2019 · To calculate the absorbed dose rate, we have to use in the formula: k = 5.76 x 10-7; S = 3.7 x 10 10 s-1; E = 0.662 MeV; μ t /ρ = 0.0326 cm 2 /g (values are available at NIST) μ = 1.289 cm-1 (values are available at NIST) D = 5 cm; r = 10 cm; Result: The resulting absorbed dose rate in grays per hour is then:
Aug 7, 2020 · Comparison of mean absorbed dose per unit of injected activity (Gy/GBq) calculated using RAYDOSE, VoxelMed and VoxelMed (λ RD). A Bland-Altman plot was used to compare the calculated absorbed dose in kidneys, liver and spleen doses of patients in Sample B.
Fundamentally, the computation of absorbed dose in both the MIRD and the ICRP systems is similar, as each uses the concepts of absorbed fraction, specific absorbed fraction, source and target tissue regions, reference computational phantoms, and compartmental models describing biokinetic distributions of activity in the human body.
