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UV protection, cryosurgery, topical imiquimod, and 5-FU
- Analysis of the evidence from a systematic review based on five research questions resulted in eighteen evidence-based recommendations and suggests there are several effective treatments available for AK. Strong recommendations were made for the use of UV protection, cryosurgery, topical imiquimod, and 5-FU.
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Nov 17, 2023 · Cryotherapy is the most common and effective treatment for actinic keratosis. It is most often recommended for people with single actinic keratosis lesions on the scalp or face. Some people may only need one treatment, but others require more to rid the skin of all the actinic keratosis.
- Angelica Bottaro
- 5-Fluorouracil
- Diclofenac Sodium
- Imiquimod
- Ingenol Mebutate
- Tirbanibulin Ointment
“One of the widely used and most effective prescription at-home therapies is topical chemotherapy called 5-fluorouracil,” Pratt says. Brand names for this medication include Carac, Efudex, Fluoroplex, and Tolak. Your dermatologist might suggest applying it once or twice a dayfor several weeks. Depending on the extent of your actinic keratosis, they...
Diclofenac sodium gel (Solaraze, Cambia, Voltaren) is a topical nonsteroidal anti-inflammatory drug (NSAID)that can help treat actinic keratosis. It’s not clear why it helps reduce the appearance of skin lesions. You’ll typically apply it twice a dayTrusted Sourcefor 2 to 3 months. If you notice any unwanted side effects, it’s best to let your doct...
You may get a prescription for this medication if you have actinic keratoses on your face and scalp. This medication works by affecting your body’s immune response to skin lesions. In basic terms, it prompts your immune system to release cytokines, which can cause inflammation that helps destroy the actinic keratosis lesions. When using this medica...
You’ll apply this medication gel once a dayfor 2 or 3 days in a row and leave it on for about 6 hours before washing it off. Your dermatologist will give you more specific, personalized directions on using this treatment.
This treatment is typically used on the face and scalp. Research from 2021suggests it may cause fewer side effects than 5-fluorouracil, diclofenac, and imiquimod. Generally, you’ll apply it directly to the affected skin once a day for 5 days in a row. Avoid applying it anywhere other than the areas your dermatologist told you to treat.
- Sian Ferguson
Feb 23, 2022 · If you find a spot or growth on your skin that you think could be an actinic keratosis (AK), it’s time for a thorough skin exam. Should you have an AK, an accurate diagnosis and treatment can: Reduce your risk of developing skin cancer. Get rid of an AK, replacing it with new, healthy-looking skin.
Jul 7, 2022 · However, no gold standard treatment has been established. We aimed to investigate the management of AK by comparing the effectiveness and treatment duration of treatment modalities, including cryotherapy, imiquimod (IMQ), and photodynamic therapy (PDT).
- 10.3390/jcm11143953
- 2022/07
- J Clin Med. 2022 Jul; 11(14): 3953.
Jun 7, 2021 · Treatment options for AK include topical medications, photodynamic therapy, cryosurgery, and laser ablation. Objective. This executive summary provides a synopsis of the 18 evidence-based recommendations for the treatment of AK detailed in the Guidelines of Care for the Management of Actinic Keratosis. Methods.
- Daniel B. Eisen, Maryam M. Asgari, Daniel D. Bennett, Suzanne M. Connolly, Robert P. Dellavalle, Est...
- 2021
Strong recommendations are made for using ultraviolet protection, topical imiquimod, topical 5-fluorouracil, and cryosurgery. Conditional recommendations are made for the use of photodynamic therapy and diclofenac for the treatment of AK, both individually and as part of combination therapy regimens.
Feb 19, 2022 · A recent study evaluated the efficacy of four treatments (5% imiquimod cream, methyl aminolevulinate PDT [MAL-PDT], 5% 5-FU cream, and 0.015% ingenol mebutate gel [IGM]) for AK located on the head and neck. Results showed that 5% 5-FU cream was the most effective among the field-directed treatments.
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