Yahoo Web Search

Search results

1. www.mayoclinic.org › diseases-conditions › breastBreast cancer - Symptoms and causes - Mayo Clinic

   www.mayoclinic.org › diseases-conditions › breast

   • Cached

   Feb 10, 2024 · Breast cancer is a kind of cancer that begins as a growth of cells in the breast tissue. After skin cancer, breast cancer is the most common cancer diagnosed in women in the United States. But breast cancer doesn't just happen in women. Everyone is born with some breast tissue, so anyone can get breast cancer.

2. news.harvard.edu › gazette › storyEstrogen a more powerful breast cancer culprit than we ...

   news.harvard.edu › gazette › story

   • Cached

   May 17, 2023 · Estrogen is already known to fuel breast cancer growth by promoting the proliferation of breast cells. However, the new observations cast this hormone in a different light. They show estrogen is a more central character in cancer genesis because it directly alters how cells repair their DNA.

3. People also ask

   How does breast cancer happen?

   • It's likely that breast cancer happens through a complex interaction of your genetic makeup and the world around you. Healthcare professionals know that breast cancer starts when something changes the DNA inside cells in the breast tissue. A cell's DNA holds the instructions that tell a cell what to do.

   Breast cancer - Symptoms and causes - Mayo Clinic

   www.mayoclinic.org/diseases-conditions/breast-cancer/symptoms-causes/syc-20352470

   See all results for this question

   What happens when breast cancer spreads?

   • When cancer spreads, it's called metastatic cancer. The DNA changes that lead to breast cancer most often happen in the cells that line the milk ducts. These ducts are tubes designed to carry milk to the nipple. Breast cancer that starts in the ducts is called invasive ductal carcinoma.

   Breast cancer - Symptoms and causes - Mayo Clinic

   www.mayoclinic.org/diseases-conditions/breast-cancer/symptoms-causes/syc-20352470

   See all results for this question

   How does estrogen affect breast cancer cells?

   • In hormone-receptor (ER+) positive/HER2-negative “luminal” breast cancers, malignant cells generally retain dependence on estrogen for its mitogenic effects. Estrogen binding to hormone receptors initiates a signal transduction pathway that culminates in receptor-driven expression of genes promoting cell growth, survival and proliferation.

   Targeting the cell cycle in breast cancer: towards the next phase

   www.ncbi.nlm.nih.gov/pmc/articles/PMC6152498/

   See all results for this question

4. www.ncbi.nlm.nih.gov › pmc › articlesSystemic Actions of Breast Cancer Facilitate Functional ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Jan 13, 2020 · The systemic effects of breast cancer can lead to functional limitations in patients who suffer from muscle weakness, fatigue, pain, fibromyalgia, or many other dysfunctions, which hasten cancer-associated death.

   • Author: Ruizhong Wang, Harikrishna Nakshatri
   • DOI: 10.3390/cancers12010194

   • Publish Year: 2020
   • Publication: Cancers (Basel). 2020 Jan; 12(1): 194.

5. www.ncbi.nlm.nih.gov › pmc › articlesTargeting the cell cycle in breast cancer: towards the next phase

   www.ncbi.nlm.nih.gov › pmc › articles

   Sep 11, 2018 · Deregulation of the cell cycle is a hallmark of cancer that enables limitless cell division. To support this malignant phenotype, cells acquire molecular alterations that abrogate or bypass control mechanisms in signaling pathways and cellular checkpoints that normally function to prevent genomic instability and uncontrolled cell proliferation.

   • Author: KL Thu, I Soria-Bretones, TW Mak, DW Cescon
   • DOI: 10.1080/15384101.2018.1502567

   • Publish Year: 2018
   • Publication: Cell Cycle. 2018; 17(15): 1871-1885.

6. Top Stories

   • Nature

     Nuclear receptors — studying genes to understand hormones - Nature Reviews Genetics

     Ligand-bound receptors undergo conformational changes to facilitate binding both to DNA and to co-factors that facilitate interactions with....

     6 days ago

   View all

7. www.ncbi.nlm.nih.gov › pmc › articlesImmune System Effects on Breast Cancer - PMC

   www.ncbi.nlm.nih.gov › pmc › articles

   Jun 3, 2021 · Until recently, it has been considered that breast cancer elicits a small immune response. However, it is now clear that breast tumor progression is either prevented by the action of antitumor immunity or exacerbated by proinflammatory cytokines released mainly by the immune cells.

   • Author: Jensen N. Amens, Gökhan Bahçecioglu, Pinar Zorlutuna
   • DOI: 10.1007/s12195-021-00679-8

   • Publish Year: 2021
   • Publication: Cell Mol Bioeng. 2021 Aug; 14(4): 279-292.

8. www.ucsfhealth.org › education › basic-facts-aboutBasic Facts About Breast Health: Breast Cancer Biology

   www.ucsfhealth.org › education › basic-facts-about

   • Cached

   How Does Cancer Spread? A malignant tumor can invade surrounding tissue and destroy it. Cancer cells also can break away from a malignant tumor and enter the bloodstream or lymphatic system. This is how cancer spreads within the body. When breast cancer spreads outside the breast, cancer cells often are found in the lymph nodes under the arm.

9. www.urmc.rochester.edu › encyclopedia › contentBreast Cancer: Overview - Health Encyclopedia - University of ...

   www.urmc.rochester.edu › encyclopedia › content

   • Cached

   Search Encyclopedia. Breast Cancer: Overview. What is breast cancer? Cancer is when cells in the body change and grow out of control. In most cancer types, the changed (abnormal) cells often grow to form a lump or mass called a tumor. Cancer cells can also grow into (invade) nearby areas. And they can spread to other parts of the body.