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  1. Jun 7, 2022 · Neonatal outcomes of infants born to mothers with von Willebrand disease (VWD) in comparison to mothers without VWD.

  2. Aug 28, 2023 · Continuing Education Activity. Von Willebrand disease is a bleeding disorder caused by the qualitative or quantitative deficiency of the pro-von Willebrand factor. Affected people may complain of excessive bruising, prolonged bleeding from mucosal surfaces, and prolonged bleeding after minor trauma.

    • Ayan Sabih, Hani M. Babiker
    • 2023/08/28
    • 2019
  3. Nov 16, 2012 · Outcomes. The baby was ventilated for 72 hours, a central line was inserted for venous access and administration of Wilate. Subsequent factor assays (with out FFP) reveal FVIII <1 iu/dl and vWF <1 iu/dl.

    • Oliver Hegener, Jemma Efford, Jack L Bartram, Lesley Henderson, Kate Khair
    • 2012
  4. Sep 15, 2022 · Results: HMB was recorded after cohort entry in 388 of 1,335 women (29.1%) with VWD and 1,524 of 12,463 women (12.2%) without VWD. The cumulative incidence of HMB was higher in women with versus without VWD across all ages ( p < 0.0001), and irrespective of prior HMB status ( p < 0.001).

    • 10.1089/jwh.2022.0082
    • September 2022
  5. Nov 24, 2016 · The symptoms of von Willebrand’s disease vary among patients, depending on the level of residual von Willebrand factor activity, the disease subtype, and to some extent, age and sex.

    • Frank W G Leebeek, Jeroen C J Eikenboom
    • 2016
  6. Diagnose the patient with type 1 VWD and send targeted genetic testing. The panel recommends a VWF level of <0.30 IU/mL regardless of bleeding, and in patients with abnormal bleeding, a VWF level of <0.50 IU/mL to confirm the diagnosis of type 1 VWD (Strong recommendation, low certainty).

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  8. Jan 10, 2022 · Abstract. von Willebrand disease (VWD) disproportionately affects women because of the potential for heavy menstrual bleeding (HMB), delivery complications, and postpartum hemorrhage (PPH). To systematically synthesize the evidence regarding first-line management of HMB, treatment of women requiring or desiring neuraxial analgesia, and ...

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