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      • No cases of stillbirth or early neonatal death were observed in women with VWD. Conclusion Although women with VWD did not demonstrate an increased risk of vaginal bleeding during pregnancy or poor fetal outcomes, they had a higher risk of primary postpartum hemorrhage and requiring blood transfusion.
      www.mdpi.com › 1648/9144/58-6 › 774

      The Effect of Von Willebrand Disease on Pregnancy, Delivery ...

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  3. www.ncbi.nlm.nih.gov › pmc › articlesImpact of von Willebrand Disease on Women's Health Outcomes: A...

    Sep 15, 2022 · Results: HMB was recorded after cohort entry in 388 of 1,335 women (29.1%) with VWD and 1,524 of 12,463 women (12.2%) without VWD. The cumulative incidence of HMB was higher in women with versus without VWD across all ages ( p < 0.0001), and irrespective of prior HMB status ( p < 0.001).

    • 10.1089/jwh.2022.0082
    • September 2022

  4. www.ncbi.nlm.nih.gov › pmc › articlesThe Effect of Von Willebrand Disease on Pregnancy, Delivery ...

    Jun 7, 2022 · Neonatal outcomes of infants born to mothers with von Willebrand disease (VWD) in comparison to mothers without VWD.

  5. ashpublications.org › hematology › articleWhat have we learned about the patient's experience of von ...

    Dec 9, 2022 · Von Willebrand disease (VWD), the most common inherited bleeding disorder (IBD), disproportionately affects females, given the hemostatic challenges they may encounter throughout their lifetimes. Despite this, research about VWD remains grossly underrepresented, particularly compared to hemophilia, which is historically diagnosed in males.

  6. ashpublications.org › blood › articlevon Willebrand disease: what does the future hold? | Blood ...

    Apr 29, 2021 · Bleeding-related hospitalization in patients with von Willebrand disease and the impact of prophylaxis: Results from national registers in Sweden compared with normal controls and participants in the von Willebrand Disease Prophylaxis Network.

    • Cécile V Denis, Sophie Susen, Peter J Lenting
    • 2021

  7. www.nejm.org › doi › fullVon Willebrand’s Disease | New England Journal of Medicine

    Nov 24, 2016 · The symptoms of von Willebrand’s disease vary among patients, depending on the level of residual von Willebrand factor activity, the disease subtype, and to some extent, age and sex.

    • Frank W G Leebeek, Jeroen C J Eikenboom
    • 2016

  8. onlinelibrary.wiley.com › doi › fullPregnancy and delivery in women with von Willebrand disease

    May 20, 2019 · 7 GENERAL GUIDELINES FOR THE TREATMENT OF WOMEN WITH VON WILLEBRAND DISEASE AT DELIVERY. Since pregnant women with VWD are at increased risk of PPH if untreated, 9, 17, 27, 31 treatment options should be planned during pregnancy.

  9. ashpublications.org › bloodadvances › articleGynecologic and obstetric management of women with von ...

    Jan 10, 2022 · Abstract. von Willebrand disease (VWD) disproportionately affects women because of the potential for heavy menstrual bleeding (HMB), delivery complications, and postpartum hemorrhage (PPH). To systematically synthesize the evidence regarding first-line management of HMB, treatment of women requiring or desiring neuraxial analgesia, and ...

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