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Can't be cured
- Von Willebrand disease can't be cured. But with treatment and self-care, most people with this disease can lead active lives.
www.mayoclinic.org › diseases-conditions › von-willebrand-disease
Dec 18, 2023 · The treatment of von Willebrand disease (VWD) varies depending on the type and severity of the condition. The main goal is to prevent or control bleeding episodes.
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Diagnose the patient with type 1 VWD and send targeted genetic testing. The panel recommends a VWF level of <0.30 IU/mL regardless of bleeding, and in patients with abnormal bleeding, a VWF level of <0.50 IU/mL to confirm the diagnosis of type 1 VWD (Strong recommendation, low certainty).
Nov 12, 2019 · Introduction. Patients with VWD, the most frequent inherited bleeding disorder together with hemophilia A, are enjoying excellent treatment and a life expectancy at birth similar to that of men and women in the general population, at least in high-income countries.
- Pier Mannuccio Mannucci
- 2019
Von Willebrand Disease (VWD), the most common inherited bleeding disorder, is defined by decreased activity of von Willebrand Factor (VWF) activity in the blood. This can be secondary to a quantitative or qualitative defect.
- Angela C. Weyand, Veronica H. Flood
- 2021/12
- 10.1016/j.hoc.2021.07.004
Apr 29, 2021 · The clinical management of VWD has remained essentially unchanged over the last 30 years or so, using von Willebrand factor (VWF) concentrates, desmopressin, and anti–fibrinolytic agents as main tools to control bleeding. This is in contrast to hemophilia A, for which a continuous innovative path has led to novel treatment modalities.
- Cécile V Denis, Sophie Susen, Peter J Lenting
- 2021
Sep 29, 2022 · In this review, we aim to provide an overview of (1) the regulation of VWF expression with a specific focus on inflammation and (2) the contribution of inflammation-induced VWF release to in situ thrombosis. Finally, we will evaluate pharmacological strategies to target VWF.
Aug 28, 2023 · Continuing Education Activity. Von Willebrand disease is a bleeding disorder caused by the qualitative or quantitative deficiency of the pro-von Willebrand factor. Affected people may complain of excessive bruising, prolonged bleeding from mucosal surfaces, and prolonged bleeding after minor trauma.
