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Sir Ernst Boris Chain FRS FRSA (19 June 1906 – 12 August 1979) was a German-born British biochemist and co-recipient of the Nobel Prize in Physiology or Medicine for his work on penicillin.
Jun 15, 2024 · Sir Ernst Boris Chain was a German-born British biochemist who, with pathologist Howard Walter Florey, isolated and purified penicillin (which had been discovered in 1928 by Sir Alexander Fleming) and performed the first clinical trials of the antibiotic.
- The Editors of Encyclopaedia Britannica
Ernst Boris Chain. Nobel Prize in Physiology or Medicine 1945 for the discovery of penicillin and its curative effect in various infectious diseases, shared with Sir Alexander Fleming and Sir Howard Walter Florey. Department of Biochemistry PhD student (1933-1935).
May 2, 2023 · Its unique structure is crucial for its ability to kill bacteria, and understanding this structure is essential for the development of new and more effective antibiotics. Here are the key points about the structure: Penicillin contains a beta-lactam ring and a thiazolidine ring.
Jun 22, 2013 · Chain directed the microbiological methods for producing penicillin and the chemical engineering methods to extract the material. This technology was transferred to US government facilities in 1941 for commercial production of penicillin, becoming an important element in the Allied war effort.
- Nelson Kardos, Arnold L. Demain
- 2013
This led to his best known work, the reinvestigation of penicillin, which had been described by Sir Alexander Fleming nine years earlier, and to the discovery of its chemotherapeutic action. Later he worked on the isolation and elucidation of the chemical structure of penicillin and other natural antibiotics.
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Mar 27, 2020 · Howard Walter Florey (1898–1968) and Ernst Boris Chain (1906–1979) were the scientists who followed up most successfully on Alexander Fleming’s discovery of penicillin, sharing with him the 1945 Nobel Prize in Physiology or Medicine.
