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  1. Our initial advisory panel convened scientific experts, including Professor Fiona Watt, Professor David Adams and Professor Nishi Chaturvedi, to select the most promising projects out of 75 teams from around the world. The Big Beat Challenge is a £30 million research award to revolutionise the prevention, diagnosis or treatment of heart and ...

  2. The Big Beat Challenge is a global competition for a single award of up to £30m. It is designed to spur the international research community to identify an opportunity for game-changing innovation in heart and circulatory science or medicine, that wouldn’t be possible without funding on this scale.

    • Hybrid Heart
    • IMAP
    • Echoes
    • Cureheart

    Led by Professor Jolanda Kluin at the University of Amsterdam, Netherlands, the Hybrid Heart team hope to create a soft robotic heart to cure heart failure. Their vision is that this could replace the need for human heart transplants and give hope to those desperately waiting for a donated organ.

    With BHF Professor Ziad Mallat from the University of Cambridge at the helm, the iMAP team want to build a detailed molecular map of atherosclerotic plaques - the fatty deposits that develop in arteries. Their aim is to reveal new ways to combat atherosclerosis. This could lead to a new wave of medicines and vaccines that can prevent heart attacks ...

    Alongside his team in Belgium, Professor Frank Rademakers at KU Leuven, Belgium, aims to develop wearable technology that can be used in daily life to capture more data than ever, from symptoms and physical activity to heart function and air quality. All this information could be used alongside genetic and healthcare data to transform the diagnosis...

    Led by BHF Professor Hugh Watkins at the University of Oxford, the CureHeart team want to develop a treatment that targets and silences the faulty genes responsible for cardiomyopathies. These are diseases of the heart muscle that can cause young people to suddenly die or develop heart failure at an early age. Their aim is to halt the progression o...

  3. Betting big, without borders. The BHF is betting that the open-minded design of The Big Beat Challenge will return their investment in a big way. Founded in 1961, the charity funds about GBP 100 million (USD 131 million) in CVD research per year, making it one of the world's largest independent funders in this area.

  4. Sep 24, 2022 · Big Beat Challenge is the biggest single research award made to date by the BHF, a 61-year-old medical research charity that is the largest independent funder of cardiovascular research in Europe. It is also the charity’s first award that will support overseas components of a multinational research programme.

  5. Jul 29, 2022 · 29th July 2022. A project to develop genetic therapies to effectively cure cardiomyopathy has been announced as the winner of the British Heart Foundation’s Big Beat Challenge, a £30 million innovation project targeting unmet needs in heart disease.

  6. Mar 3, 2020 · Today, cardiovascular diseases are the number one cause of death globally. Despite advances in research, one person in the United Kingdom dies from heart and circulatory problems every three minutes. Launched in August 2018, the global Big Beat Challenge, which offers a single research award of £30 million (€34 million), has inspired the ...

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