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Nov 24, 2016 · Von Willebrand's disease is the most common inherited bleeding disorder and is generally transmitted as an autosomal dominant trait. It is mainly associated with mucosal bleeding and...
Von Willebrand disease (VWD) is the most common hereditary blood-clotting disorder in humans. An acquired form can sometimes result from other medical conditions. It arises from a deficiency in the quality or quantity of von Willebrand factor (VWF), a multimeric protein that is required for platelet adhesion. It is known to affect several ...
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Von Willebrand disease is classified into 3 main types: Type 1: A quantitative deficiency of VWF, which is the most common form and is an autosomal dominant disorder. VWD concentration and activity are both reduced proportionally.
Jan 1, 2022 · von Willebrand disease (VWD) is the most common inherited bleeding disorder and is the result of either quantitative (Type 1 and Type 3) or qualitative defects (Type 2) in von Willebrand factor (VWF). 1 Patients with VWD are at particular risk of hemorrhage in the perioperative setting, given the key role of VWF in both hemostasis 2 and wound ...
- 10.1182/bloodadvances.2021005666
- 2022/01/01
- Blood Adv. 2022 Jan 11; 6(1): 121-128.
Feb 1, 2011 · Abstract. Abstract: von Willebrand disease is a common inherited bleeding disorder characterized by excessive mucocutaneous bleeding. Characteristic bleeding symptoms include epistaxis, easy ...
- Paula D James, Anne C Goodeve
- 2011
Von Willebrand disease (VWD) is a common bleeding disorder, affecting males and females equally, that often manifests in mucosal bleeding. VWD can be secondary to a quantitative (Type 1 and Type 3) or qualitative (Type 2) defects in Von Willebrand factor.
Dec 5, 2016 · Abstract. von Willebrand disease (vWD) is the most common inherited disorder of hemostasis and comprises a spectrum of heterogeneous subtypes. Significant advances have been made in understanding von Willebrand factor ( vWF) gene mutations, resultant physiologic deficits in the vWF peptide, and their correlation to clinical presentation.
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related to: jutta von brandenburg von karman willebrand typeSee official information about a von Willebrand disease treatment for adults.
