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1. pubmed.ncbi.nlm.nih.gov › 12883448Von Willebrand factor in type 1 diabetes: its production and...

   pubmed.ncbi.nlm.nih.gov › 12883448

   Results: Von Willebrand factor was significantly increased in diabetic patients compared to controls (median 100% vs 87%, p=0.001). Von Willebrand factor activity was significantly higher in diabetic patients with micro/macroalbuminuria than those with normoalbuminuria (109% vs 93%, p<0.001).

2. diabetesjournals.org › care › articlevon Willebrand Factor and Endothelial Abnormalities in ...

   diabetesjournals.org › care › article

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   Feb 1, 1991 · We briefly summarize current knowledge on 1) the abnormalities of von Willebrand factor (vWF) as an indicator of endothelial cell (EC) dysfunction in diabetes and 2) the modifications induced in the growth of cultured ECs by high glucose in the incubation media.

3. People also ask

   What is von Willebrand disease type 1?

   • Sadler, JE. Von Willebrand disease type 1: a diagnosis in search of a disease. Blood 2003;101:2089-2093 54. Gudmundsdottir, BR, Marder, VJ, Onundarson, PT. Risk of excessive bleeding associated with marginally low von Willebrand factor and mild platelet dysfunction.

   Von Willebrand’s Disease | New England Journal of Medicine

   www.nejm.org/doi/full/10.1056/NEJMra1601561

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   Is vWD a type 2 defect in von Willebrand factor?

   • VWD can be secondary to a quantitative (Type 1 and Type 3) or qualitative (Type 2) defects in Von Willebrand factor. Initial testing includes VWF antigen, as well as a platelet binding assay to differentiate between qualitative and quantitative defects.

   Von Willebrand Disease: Current Status of Diagnosis and Management

   www.ncbi.nlm.nih.gov/pmc/articles/PMC8919990/

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   What is Type 3 von Willebrand's disease?

   • Type 3 von Willebrand’s disease is rare (accounting for <5% of cases), is the most severe form, and is caused by the absence of circulating von Willebrand factor. Pathophysiological Mechanisms and Classification of von Willebrand’s Disease.

   Von Willebrand’s Disease | New England Journal of Medicine

   www.nejm.org/doi/full/10.1056/NEJMra1601561

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   What is the phenotype of type 2 von Willebrand's disease?

   • In type 2 von Willebrand’s disease, the phenotype is determined by specific functional defects or characteristics of the von Willebrand factor protein, and consequently, the mutations are usually dominant-negative missense mutations restricted to specific domains of von Willebrand factor.

   Von Willebrand’s Disease | New England Journal of Medicine

   www.nejm.org/doi/full/10.1056/NEJMra1601561

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4. www.ncbi.nlm.nih.gov › pmc › articlesVon Willebrand Disease: Current Status of Diagnosis and ...

   www.ncbi.nlm.nih.gov › pmc › articles

   VWD can be due to a quantitative or qualitative deficiency of VWF and is subdivided into types based on the underlying defect. Type 1 and 3 are quantitative defects with Type 1 defined as a partial deficiency and Type 3 resulting from an absolute deficiency of VWF. Type 1 includes Type 1C, a subtype defined by increased clearance of VWF.

   • Author: Angela C. Weyand, Veronica H. Flood
   • Published: 2021/12

   • DOI: 10.1016/j.hoc.2021.07.004

5. www.nejm.org › doi › fullVon Willebrand’s Disease | New England Journal of Medicine

   www.nejm.org › doi › full

   Nov 24, 2016 · For most patients who have type 1 von Willebrand’s disease or who are classified as having a low level of von Willebrand factor or possible type 1 von Willebrand’s disease,...

   • Author: Frank W G Leebeek, Jeroen C J Eikenboom

   • Publish Year: 2016

6. ashpublications.org › thehematologist › articleProgress in the Diagnosis and Management of Type 1 von ...

   ashpublications.org › thehematologist › article

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   Nov 18, 2014 · According to the National Heart, Lung, and Blood Institute (NHLBI) Guidelines 2 and a recent publication by the British Committee for Standards in Haematology, 3 a definitive diagnosis of type 1 VWD requires a VWF ristocetin cofactor (VWF:RCo) and/or a VWF antigen (VWF:Ag) of < 30 IU dL -1.

   • Author: Robert Montgomery, Jonathan Roberts, Gilbert C. White Ii

   • Publish Year: 2014

7. diabetesjournals.org › clinical › articleGood to Know: Type 1 Diabetes | Clinical Diabetes | American ...

   diabetesjournals.org › clinical › article

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   Jul 1, 2021 · Type 1 diabetes affects about 5% of people with diabetes in the United States. In the past, type 1 diabetes was called juvenile diabetes or insulin-dependent diabetes. It’s usually first diagnosed in young people, but it can occur at any age. Type 1 diabetes is much less common than type 2 diabetes.

8. www.pennmedicine.org › von-willebrand-diseaseVon Willebrand Disease – Symptoms and Causes | Penn Medicine

   www.pennmedicine.org › von-willebrand-disease

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   Von Willebrand Disease Types and Von Willebrand Factor. There are three types of VWD, depending on how von Willebrand factor is affected: Type 1: With Type 1, people still produce von Willebrand factor, but at lower amounts. It’s the mildest and most common form of the condition.