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Mar 4, 2022 · Summary. Von Willebrand disease (VWD) is the most common hereditary bleeding disorder in dogs and people, and the trait has been identified in many other species. The disease is heterogeneous, caused by a variety of defects in von Willebrand factor (VWF) protein that influence bleeding severity and complicate clinical diagnosis and management.
Dec 22, 2017 · von Willebrand disease (vWD) is the most common type of extrinsic platelet disorder and the most commonly found inherited coagulopathy in dogs. 1 Although vWD is closely associated with Doberman Pinschers, the disease has been identified in 54 breeds. 14,15 It was first reported in 1970 in a family of German Shepherd Dogs with clinical signs ...
- Julian Alejandro Crespi, Laura Soledad Barrientos, Guillermo Giovambattista
- 10.1177/1040638717750429
- 2018
- J Vet Diagn Invest. 2018 Mar; 30(2): 310-314.
Dec 1, 1992 · Canine von Willebrand's disease is the most common inherited bleeding disorder of purebred dogs and blood component therapy provides the most effective transfusion support for severely affected dogs. Canine von Willebrand's disease (vWD) is the most common inherited bleeding disorder of purebred dogs. Optimum treatment of affected dogs is influenced by the presence of concurrent disorders ...
Von Willebrand Disease (vWD) is an inherited bleeding disorder that makes it difficult for blood to clot. It is the most common inherited bleeding disorder in dogs, and it can be seen more frequently in certain breeds, such as Doberman Pinschers. Dogs with vWD may show signs of bleeding, such as skin bruising, bleeding from the gums or nose ...
Heterozygosity is often lethal in this form of VWD, in which both homozygotes and heterozygotes can manifest a bleeding tendency. Von Willebrand's disease (VWD) is the most common, mild, inherited bleeding disorder of people and animals. It is an autosomal trait with 2 forms of clinical and genetic expression. It can be a disease with autosomal recessive expression, in which clinically ...
Five cases of Von Willebrand's disease in Doberman pinscher dogs are described and the variety of clinical expressions that the disease may take are illustrated. Abstract Von Willebrand's disease is the most common inherited bleeding disorder of dogs occurring with particularly high frequency in Doberman pinscher dogs. Because of its method of transmission (autosomal incomplete dominant), the ...
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Von Williebrand Disease www.petmd.com Bleeding Disorder in Dogs Von Willebrand's Disease in Dogs Von Willebrand’s disease (vWD) is a blood disease caused by a deficiency of von Willebrand Factor (vWF), an adhesive glycoprotein in the blood required for normal platelet binding (i.e., clotting) at the sites of small blood vessel injuries.
