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Mar 4, 2022 · Summary. Von Willebrand disease (VWD) is the most common hereditary bleeding disorder in dogs and people, and the trait has been identified in many other species. The disease is heterogeneous, caused by a variety of defects in von Willebrand factor (VWF) protein that influence bleeding severity and complicate clinical diagnosis and management.
Dec 22, 2017 · von Willebrand disease (vWD) is the most common type of extrinsic platelet disorder and the most commonly found inherited coagulopathy in dogs. 1 Although vWD is closely associated with Doberman Pinschers, the disease has been identified in 54 breeds. 14,15 It was first reported in 1970 in a family of German Shepherd Dogs with clinical signs ...
- Julian Alejandro Crespi, Laura Soledad Barrientos, Guillermo Giovambattista
- 10.1177/1040638717750429
- 2018
- J Vet Diagn Invest. 2018 Mar; 30(2): 310-314.
Von Willebrand Disease (vWD) is an inherited bleeding disorder that makes it difficult for blood to clot. It is the most common inherited bleeding disorder in dogs, and it can be seen more frequently in certain breeds, such as Doberman Pinschers. Dogs with vWD may show signs of bleeding, such as skin bruising, bleeding from the gums or nose ...
Oct 1, 2009 · The Role of the von Willebrand Factor Collagen-Binding Assay (VWF:CB) in the Diagnosis and Treatment of von Willebrand Disease (VWD) and Way Beyond: A Comprehensive 36-Year History Article Feb 2023
Synopsis. Von Willebrand disease (VWD) is a common bleeding disorder, affecting males and females equally, that often manifests in mucosal bleeding. VWD can be secondary to a quantitative (Type 1 and Type 3) or qualitative (Type 2) defects in Von Willebrand factor.
- Angela C. Weyand, Veronica H. Flood
- 2021/12
- 10.1016/j.hoc.2021.07.004
May 16, 2019 · Von Willebrand disorder type I (vWDI) is known as an inherited bleeding disorder in different dog breeds following an autosomal recessive inheritance. The Kromfohrländer is a rare dog breed with an increased incidence of unclear bleeding episodes and prolonged coagulation time during/after surgery or injuries, indicating a defect in one or more critical proteins of the coagulation cascade.
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Jan 1, 2021 · von Willebrand disease (VWD) is a common bleeding disorder, which affects 1 in 100 individuals based on laboratory testing and at least 1 in 1000 individuals based on presence of abnormal bleeding symptoms. 1, 2 VWD was first described almost 100 years ago, and since the initial report, major advances in both diagnostic testing and treatment ...
