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Dec 22, 2017 · von Willebrand disease (vWD) is the most common inherited coagulopathy in dogs, particularly in Doberman Pinschers. We developed a pyrosequencing-based assay to estimate the frequency of the c.7437G>A mutation associated with vWD type 1 in the Doberman Pinscher population of Buenos Aires, Argentina.
- Julian Alejandro Crespi, Laura Soledad Barrientos, Guillermo Giovambattista
- 10.1177/1040638717750429
- 2018
- J Vet Diagn Invest. 2018 Mar; 30(2): 310-314.
A von Willebrand’s factor genomic nucleotide variant and polymerase chain reaction diagnostic test associated with inheritable type-2 von Willebrand’s disease in a line of German short-haired pointer dogs.
- H. J. Burgess, J. P. Woods, A. C. G. Abrams-Ogg, R. D. Wood
- Can J Vet Res. 2009 Oct; 73(4): 252-259.
- 2009
- 2009/10
Oct 1, 2009 · Diagnostic tests revealed Type III von Willebrand's disease and primary hypothyroidism leading to an acute hypothyroid crisis and acquired factor VIII (FVIII) deficiency.
Mar 4, 2022 · Von Willebrand disease (VWD) is the most common hereditary bleeding disorder in dogs and people, and the trait has been identified in many other species. The disease is heterogeneous, caused by a variety of defects in von Willebrand factor (VWF) protein that influence bleeding severity and complicate clinical diagnosis and management.
Von Willebrand Disease (vWD) is an inherited bleeding disorder that makes it difficult for blood to clot. It is the most common inherited bleeding disorder in dogs, and it can be seen more frequently in certain breeds, such as Doberman Pinschers.
Von Willebrand disease (VWD) is a common bleeding disorder, affecting males and females equally, that often manifests in mucosal bleeding. VWD can be secondary to a quantitative (Type 1 and Type 3) or qualitative (Type 2) defects in Von Willebrand factor.
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May 16, 2019 · We identified the G > A von Willebrand type I mutation in 80.5% of our study population. 65.5% were heterozygous (WT/MUT) and 15.0% were homozygous for the mutation (MUT/MUT). 21% of the overall study population exhibited bleeding symptoms. 45.5% of all homozygous dogs (MUT/MUT) showed bleeding symptoms.
