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Von Willebrand's disease (vWD) is the most common inherited bleeding disorder of both humans and dogs. It is caused by a deficiency in the amount of a specific protein needed to help platelets (the blood cells used in clotting) stick together and form clots to seal broken blood vessels. The deficient protein is called von Willebrand factor (vWF).
Nov 12, 2019 · Lenalidomide as a novel therapy for gastrointestinal angiodysplasia in von Willebrand disease. Haemophilia. 2018;24(2):278-282. [ PubMed] [ Google Scholar] 40. Stockschlaeder M, Schneppenheim R, Budde U. Update on von Willebrand factor multimers: focus on high-molecular-weight multimers and their role in hemostasis.
- Pier Mannuccio Mannucci
- 2019
Nov 17, 2017 · The problem of diagnosing von Willebrand disease (VWD) is well known and has spawned a proliferation of guidelines. 1 - 3 The problem relates mainly to the diagnosis of milder forms of type 1 VWD and their distinction from “low VWF” levels which may contribute to bleeding risk but not cause VWD. 4 The question “can you grow out of VWD ...
- M. Laffan
- 2017
Von Willebrand disease (VWD) constitutes the most common inherited human bleeding disorder. It is associated with a mucocutaneous bleeding phenotype that can significantly impact upon quality of life. In spite of its prevalence and associated morbidity, the diagnosis and sub-classification of VWD continue to pose significant clinical challenges.
- Helen Fogarty, Dearbhla Doherty, James S. O'Donnell, James S. O'Donnell
- 10.1111/bjh.16681
- 2020
- 2020/11
Background. von Willebrand Disease (abbreviated vWD) is an inherited bleeding disorder caused by lack of von Willebrand factor protein (vWF). This protein circulates in the blood stream and must be present at the site of blood vessel injury in order to control bleeding from that vessel. Von Willebrand disease is a distinct disorder, it is not ...
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Mar 11, 2024 · Von Willebrand disease is a bleeding disorder that affects some purebred dogs. It causes problems with how your dog’s blood clots, putting them at risk for unusually heavy bleeding. It's common ...
Von Willebrand Disease (vWD) is an inherited bleeding disorder that makes it difficult for blood to clot. It is the most common inherited bleeding disorder in dogs, and it can be seen more frequently in certain breeds, such as Doberman Pinschers. Dogs with vWD may show signs of bleeding, such as skin bruising, bleeding from the gums or nose ...
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