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  1. May 15, 2024 · Key points. With proper care, women with von Willebrand disease (VWD) can have a successful pregnancy and deliver a healthy child. Close monitoring throughout pregnancy is important for women with VWD. Women with VWD are at risk for serious bleeding after delivery. Pregnancy and childbirth.

  2. May 20, 2019 · The variable pattern of changes observed during pregnancy of von Willebrand factor (VWF) and factor VIII (FVIII), the protein carried by VWF, prompts a careful evaluation of pregnant women with VWD to plan the most appropriate treatment at the time of parturition.

    • Giancarlo Castaman, Paula D. James
    • 2019
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  4. General guidelines for the treatment of women with von Willebrand disease at delivery. Since pregnant women with VWD are at increased risk of postpartum hemorrhage if untreated 9, 17, 27, 31, treatment options should be planned at the beginning of pregnancy.

    • Giancarlo Castaman, Paula D. James
    • 10.1111/ejh.13250
    • 2019
    • 2019/08
  5. 1. refer to a center that has high-risk obstetrics capabilities and with expertise in hemostasis for prenatal care, delivery, termination of pregnancy, or management of miscarriage. (C, IV) 2. administer prophylaxis with DDAVP or VWF concentrate before invasive procedures.

    • 308KB
    • 8
  6. May 1, 2017 · Adapted from the ASH Quick Reference Pocket Guide: 2012 Clinical Practice Guideline on the Evaluation and Management of von Willebrand Disease. Laboratory Diagnosis of vWD in Pregnancy. Given the hormonal changes that occur during pregnancy, the diagnosis can be obscured and is ideally made prior to conception.

    • Caroline Berube, Brian Dietrich
    • 2017
  7. von Willebrand disease is caused by either a quantitative or qualitative defect in von Willebrand factor (VWF). Patients may have extensive mucosal bleeding (because of plate-let dysfunction) and prolonged bleeding after surgery (because of factor VIII deficiency).

  8. May 8, 2017 · Monday, May 8, 2017. Von Willebrand's Disease and Pregnancy: A Single Center Experience [10K] Beck, Stacy M. MD; Samuels, Philip MD; Huang, Ying; Kraut, Eric MD; Wang, Tzu-Fei MD. Author Information. Obstetrics & Gynecology: May 2017 - Volume 129 - Issue 5 - p 114S. doi: 10.1097/01.AOG.0000514603.48065.a1. Buy. Metrics. Abstract. INTRODUCTION:

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