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The variable pattern of changes observed during pregnancy of von Willebrand factor (VWF) and factor VIII (FVIII), the protein carried by VWF, prompts a careful evaluation of pregnant women with VWD to plan the most appropriate treatment at the time of parturition.
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Given the wide heterogeneity of phenotypes and of the...
- Mcmdm-1Vwd
Introduction. von Willebrand factor (VWF) is a multimeric...
- Table 1
Jun 7, 2022 · Although VWD occurs equally in males and females, women are at a higher risk of being affected, mostly because of bleeding challenges associated with menstruation, pregnancy, and childbirth [ 1, 7, 8 ]. During pregnancy, many changes in hemostasis occur that result in a hypercoagulable state.
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April 2018 - Volume 16, Issue 4. Current Approaches to Pregnancy and Childbirth in Women With von Willebrand Disease. Jill M. Johnsen, MD. Associate Member. Bloodworks Northwest. Associate Professor of Medicine. Division of Hematology. University of Washington School of Medicine. Seattle, Washington. Download PDF.
May 15, 2024 · Key points. With proper care, women with von Willebrand disease (VWD) can have a successful pregnancy and deliver a healthy child. Close monitoring throughout pregnancy is important for women with VWD. Women with VWD are at risk for serious bleeding after delivery. Pregnancy and childbirth.
Sep 12, 2022 · Introduction. Inherited bleeding disorders represent a risk of bleeding during pregnancy and delivery for the carrying mother and the newborn that might inherit the disorder. Knowing the inheritance pattern of the disease is essential for prenatal counseling and development of an adequate management plan.
- Maissaa Janbain, Peter Kouides
- Int J Womens Health. 2022; 14: 1307-1313.
- 10.2147/IJWH.S273043
- 2022
Dec 10, 2021 · Pregnancy and childbirth pose an important hemostatic challenge for women with von Willebrand disease (VWD) and can be associated with an increased risk of maternal and neonatal bleeding complications.
Abstract. von Willebrand disease (VWD) is a common, inherited bleeding disorder. There are three main types of VWD, which result in a quantitative or qualitative deficiency in von Willebrand factor (VWF) and in severe cases, also Factor VIII (FVIII). The severity of bleeding depends on the underlying pathophysiology.
