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  2. See official information about a von Willebrand disease treatment for adults.

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  1. General guidelines for the treatment of women with von Willebrand disease at delivery. Since pregnant women with VWD are at increased risk of postpartum hemorrhage if untreated 9, 17, 27, 31, treatment options should be planned at the beginning of pregnancy.

    • Table 1

      Given the wide heterogeneity of phenotypes and of the...

    • Mcmdm-1Vwd

      Introduction. von Willebrand factor (VWF) is a multimeric...

  2. May 20, 2019 · In a retrospective study of 27 women with VWD, higher rates of miscarriage and bleeding throughout pregnancy were reported 9; however, caution should be exercised when interpreting these results as women with VWD may bleed more after a pregnancy complication and come to medical attention more readily.

    • Giancarlo Castaman, Paula D. James
    • 2019
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  4. Jan 10, 2022 · von Willebrand disease (VWD) disproportionately affects women because of the potential for heavy menstrual bleeding (HMB), delivery complications, and postpartum hemorrhage (PPH). To systematically synthesize the evidence regarding first-line management of HMB, treatment of women requiring or desiring neuraxial analgesia, and management of PPH.

  5. May 15, 2024 · With proper care, women with von Willebrand disease (VWD) can have a successful pregnancy and deliver a healthy child. Close monitoring throughout pregnancy is important for women with VWD. Women with VWD are at risk for serious bleeding after delivery.

  6. Nov 5, 2020 · Carriers of hemophilia A (HA) or hemophilia B (HB) and women suffering from von Willebrand disease (VWD) have an increased risk for bleeding during pregnancy and delivery. Management of these women concerns not only managing the bleeding tendency of the mother, but also that of the child with a potential bleeding disorder.

    • Frank W G Leebeek, Johannes Duvekot, Marieke J H A Kruip
    • 2020
  7. Jun 7, 2022 · Results Women with VWD were not more likely to have a miscarriage, vaginal bleeding during pregnancy, anemia, intrauterine growth restriction, or imminent premature labor.

  8. In type 1—which is the most common by far, accounting for approximately 75% of cases—the level of von Willebrand factor (VWF) is low, but the protein functions normally. In type 2, which accounts for approximately 20% of cases, the VWF level may be normal, but the protein functions abnormally.

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  2. See official information about a von Willebrand disease treatment for adults.

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