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Oct 26, 2021 · Many doctors consider desmopressin (DDAVP) the first treatment for managing von Willebrand disease. It can be used before minor surgical procedures to help control bleeding. You might be given a trial of desmopressin to make sure it's effective for you.
- Symptoms & Causes
The usual cause of von Willebrand disease is an inherited...
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Learn more about the symptoms, causes, diagnosis, treatment...
- Symptoms & Causes
Oct 26, 2021 · Von Willebrand disease is a lifelong bleeding disorder in which your blood doesn't clot properly. People with the disease have low levels of von Willebrand factor, a protein that helps blood clot, or the protein doesn't perform as it should.
Diagnose the patient with type 1 VWD and send targeted genetic testing. The panel recommends a VWF level of <0.30 IU/mL regardless of bleeding, and in patients with abnormal bleeding, a VWF level of <0.50 IU/mL to confirm the diagnosis of type 1 VWD (Strong recommendation, low certainty).
Early recognition that plasma infusions could correct the prolonged bleeding time and factor VIII deficiency in von Willebrand's disease (vWD) prompted major research efforts. Identification of the factor VIII molecule, its components, and its functions has provided critical information about replacement requirements to prevent or control bleeding.
- Louis M. Aledort
- 1991
Oct 26, 2021 · Learn more about the symptoms, causes, diagnosis, treatment of this inherited bleeding disorder in which blood doesn't clot well.
Treat-ment is tailored to the subtype of the disease: increasing plasma concentration of von Willebrand factor by releasing endogenous stores with desmopressin or replacing nonexistent or...
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Von Willebrand disease (VWD) is an inherited bleeding disorder that is caused by deficiency or dysfunction of von Willebrand factor (VWF), a plasma protein that mediates the initial adhesion of platelets at sites of vascular injury and also binds and stabilizes blood clotting factor VIII (FVIII) in the circulation. Therefore, defects in VWF can ...
