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- Exposure to things in the environment, such as viruses or chemicals, may trigger scleroderma. Immune system changes. When your immune system changes, it can trigger cells to make too much collagen in the body. Too much collagen causes patches of tight, hard skin. In some cases, developing cancer cells may trigger scleroderma. Hormones.
www.niams.nih.gov › health-topics › scleroderma
Scleroderma is an autoimmune disease that causes inflammation and thickening in the skin and other areas of the body. This inflammation leads to areas of tight, hard skin. There are two major types of scleroderma: Localized scleroderma only affects the skin and the structures directly under the skin. Systemic scleroderma, also called systemic ...
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- Types of Scleroderma
- Common Symptoms of Localized Scleroderma
- Common Symptoms of Systemic Sclerosis
- Rare Symptoms
- Complications
- Outlook For Scleroderma
- Summary
The two main categories of scleroderma include: 1. Localized scleroderma, which affects the skin and occasionally the underlying muscles or joints 2. Systemic sclerosis, which involves blood vessels and internal organs throughout the body Localized scleroderma affects mostly children and is less severe than systemic sclerosis, which is more common ...
Localized scleroderma is a rare condition. Linear scleroderma typically involves both the surface and deeper layers of the skin, but morphea scleroderma doesn't tend to go beyond the surface layers of the epidermis and dermis.
Systemic sclerosis (SSc) can affect connective tissues in many parts of the body. The two main subtypes are limited cutaneous SSc, which progresses slowly over a period of years, and diffuse cutaneous SSc, which covers more skin area and progresses more quickly to multiple organs and systems.
There are rare subtypes of localized scleroderma that can sometimes develop into more serious conditions: 1. Subcutaneous morphea affects deeper tissues and can extend deep into muscles. 2. Bullous morphea causes blister-like bumps or areas of erosion on the region of morphea. 3. Generalized morpheamay also limit joint function due to its larger co...
Scleroderma can cause many complications that range from mild to life-threatening. These usually occur when the disorder has not been treated or when treatment has failed to adequately address symptoms.
The outlook for scleroderma can vary widely from person to person. However, many people with scleroderma—particularly those with limited disease—go on to live normal lifespans. For others, life expectancy can be affected by many factors including how invasive the disease is and whether serious complications have developed. While there is no cure fo...
Scleroderma is a chronic autoimmune disease that causes inflammation and the build up of fibrous tissue in the skin and other areas of the body. The disease may be localized or systemic (affecting the whole body). Symptoms of scleroderma include thickened skin, skin color changes, stiff joints, muscle weakness, visible blood vessels, and more. Alth...
- Lana Barhum
Causes. Scleroderma results from an overproduction and accumulation of collagen in body tissues. Collagen is a fibrous type of protein that makes up your body's connective tissues, including your skin. Doctors don't know exactly what causes this process to begin, but the body's immune system appears to play a role.
Dec 21, 2023 · Causes. Doctors do not know what causes scleroderma, but they believe it to be an autoimmune condition that makes the body produce too much connective tissue. This leads to thickening, or...
- Yvette Brazier
- Doctors do not know the main causes of scleroderma. However, most believe it to be an autoimmune condition that makes the body produce too much con...
- Scleroderma can range in severity from mild to serious. Some types may relate to severe complications that can be life threatening, including heart...
- Some common early signs of scleroderma include pain, stiffness, swelling, and tightness in the fingers, hands, or feet. This may be more common in...
- The outlook for scleroderma depends on the type and severity of the condition. However, in many cases, scleroderma does not impact overall life exp...
Learn the basics of scleroderma, the different forms and the treatments physicians can use to help manage symptoms
Jun 21, 2022 · While there are different types of scleroderma, each with its own set of symptoms, the most visible manifestation of this disease is skin hardening and tightening. Organs, such as the lungs, kidneys, heart, and digestive tract, may also be affected.
What causes scleroderma? Researchers are looking into what actually causes scleroderma. We do know that this group of rare diseases is: NOT contagious. NOT a type of cancer. NOT an infection. We also know that a person develops scleroderma when the body makes too much collagen. This excess collagen is what causes the skin to thicken and harden.
