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There are no routine tests to make the diagnosis or to identify the culprit drug. Differential diagnosis includes measles, rubella, scarlet fever, non-specific toxic erythema associated with infection, Kawasaki disease, connective tissue disease and acute graft-versus-host disease.
Acute or subacute adverse cutaneous reactions to a drug or medicine include drug eruptions. There are many types of drug eruption, which range from a clinically mild and unnoticed rash to a severe cutaneous adverse reaction (SCAR) that may be life-threatening.
People also ask
What is a morbilliform rash?
How long does a morbilliform rash last?
Can antibiotics cause a morbilliform rash?
A morbilliform rash usually starts within 7–14 days of starting a new antibiotic, and lasts for 5–10 days. It may occur more quickly on re-exposure to the same drug. It can look similar to a viral exanthem but is usually pruritic , whereas similar viral rashes are not particularly itchy.
Fever and rash are the commonest signs. The rash begins as a patchy or diffuse redness (morbilliform) and progresses to small and large tense blisters because of skin swelling (oedema). Swelling of the face is a particular feature. The rash then spreads to involve the body, arms and legs. Mucous membranes are not affected.
This topic provides a differential diagnosis for urticaria and for urticaria-like conditions that resemble urticaria but are not caused by wealing. What is urticaria? Urticaria describes a group of conditions in which there are weals (or weals) in the skin, itchy white or red lumps.
Acute measles is usually confirmed on a viral nasopharyngeal or throat swab analysed by polymerase chain reaction (PCR). Blood and urine samples can also be used. This should be done within 5 days of onset of rash, however, positive results are sometimes obtained up to 10–14 days after the rash has resolved.
Recent studies suggest the actual rate of this antibiotic rash is much lower than previously reported. The drug eruption is an itchy maculopapular or morbilliform rash. It affects extensor surfaces and pressure points, face, neck, trunk, palms, and soles. It can involve the mucous membranes.
