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  1. Dec 17, 2020 · This update provides the rationale for the change in gonorrhea treatment recommendations to a higher dose (500 mg) of ceftriaxone and removal of azithromycin from the recommended regimen.

  2. May 16, 2024 · While a 2 g single oral dose of azithromycin monotherapy could treat both gonorrhea and chlamydia infections, it is not a recommended regimen due to increasing gonococcal drug resistance to azithromycin .

  3. Reflecting concern about emerging gonococcal resistance, CDC’s 2010 STD treatment guidelines recommended dual therapy for gonorrhea with a cephalosporin plus either azithromycin or doxycycline, even if NAAT for C. trachomatis was negative at the time of treatment (851)However, during 2006–2011, the minimum concentrations of cefixime needed ...

  4. Pages in this Section. Gonococcal Infections Among Adolescents and Adults. Gonococcal Infections Among Neonates. Gonococcal Infections Among Infants and Children. Next. Last Reviewed: July 22, 2021. Source: Division of STD Prevention, National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention.

  5. Apr 1, 2024 · From the 2015 Sexually Transmitted Disease (STD) guidelines, the CDC recommends treatment for a gonorrhea-chlamydia coinfection with azithromycin ( Zithromax) 1 gram given orally in a single dose, plus ceftriaxone ( Rocephin) 250 mg given intramuscularly as first-line therapy.

  6. Jul 20, 2024 · Adults with gonorrhea are treated with antibiotics. Due to emerging strains of drug-resistant Neisseria gonorrhoeae, the bacterium that causes gonorrhea, the Centers for Disease Control and Prevention recommends that uncomplicated gonorrhea be treated with the antibiotic ceftriaxone.

  7. Feb 17, 2023 · Azithromycin is an antibiotic that can treat the sexually transmitted infection (STIs) chlamydia and some of its complications, such as urethritis and cervicitis. It may also help treat...

  8. Previously, the CDC recommended a single 250-mg intramuscular dose of ceftriaxone and a single 1-g oral dose of azithromycin to treat uncomplicated gonorrhea as well as possible coinfection with Chlamydia trachomatis. However, review by CDC staff and other experts during 2018 and 2019 raised concerns about increasing drug resistance.

  9. Dec 18, 2020 · Azithromycin is no longer needed if only gonorrhea is being treated. Back in the day, we used ceftriaxone 125 mg IM. In 2010, it changed to 250 mg based on resistance patterns. Now, a decade later, we’ve increased again.

  10. Mar 2, 2022 · The ideal treatment for gonorrhea is a bacterial injection of ceftriaxone followed by an oral dose of either azithromycin or doxycycline. If you’re diagnosed with gonorrhea, talk with a healthcare provider about your health, history, and any current medications you’re taking to determine if another antibiotic treatment may be best for you.

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