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      • The ORIGIN (Outcome Reduction with Initial Glargine Intervention) trial, an open-labeled, randomized study comparing insulin glargine (the active ingredient contained in Lantus) to standard care in persons 50 years or older with abnormal glucose levels (impaired fasting glucose and/or impaired glucose tolerance) or early type 2 diabetes mellitus and established cardiovascular (CV) disease or CV risk factors, found over the course of the 6 year study, severe hypoglycemia occurred in 5.7% of...
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  2. Mar 12, 2024 · Adverse reactions associated with insulin glargine (the active ingredient contained in Lantus) include hypoglycemia, allergic reactions, injection site reactions, lipodystrophy, pruritus, rash, edema, and weight gain.

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  3. Nov 16, 2021 · Lantus can also cause hypoglycemia. So drinking alcohol with Lantus could increase your risk of hypoglycemia, especially severe hypoglycemia. Alcohol can also worsen this side...

  4. Oct 16, 2019 · Hypoglycemia, or low blood sugar, can be defined by the glucose-alert value of less than or equal to 70 mg/dL (3.9 mmol/L). 1,2 Varying blood-glucose levels can cause typical symptoms of hypoglycemia (e.g., shakiness, sweating, fatigue, hunger, headaches, and confusion) in individuals with diabetes mellitus. 3 While DI hypoglycemia typically cau...

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    • How it works. Lantus is a brand name for a type of long-acting insulin called insulin glargine. Insulin glargine is a biosynthetic human insulin analog of rDNA origin that has been made using genetic engineering technology.
    • Upsides. May be used for the treatment of type 1 diabetes in adults and children over the age of six who require long-acting insulin for their diabetes control.
    • Downsides. If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include
    • Bottom Line. Lantus is a long-acting insulin that only needs to be injected once a day, subcutaneously. It is available as a prefilled pen (Lantus Solostar) or a 10mL vial.
  5. Mar 10, 2015 · Although hypoglycemia incidence is difficult to accurately estimate, it is likely to be higher in older than younger people. In a prospective observational study of 3,810 patients in primary care, 11% of participants reported at least one episode of hypoglycemia of any severity in a 12 months period.

    • Ahmed H Abdelhafiz, Leocadio Rodríguez-Mañas, John E. Morley, Alan J Sinclair
    • 10.14336/AD.2014.0330
    • 2015
    • Aging Dis. 2015 Mar; 6(2): 156-167.
  6. Aug 23, 2022 · Often, hypoglycemia can be treated with a fast-acting sugar source, including 4 glucose tablets, 1 tube of glucose gel, or ½ a cup of fruit juice or regular soda. But if hypoglycemia isn’t treated, it can lead to unconsciousness, seizures, and even death.

  7. Feb 9, 2018 · The class of drugs known as sulphonylureas are generally not recommended, as they can cause severe hypoglycemia. Insulin detemir (Levemir) and insulin glargine (Lantus) should be used instead of NPH or human 30/70 insulin.

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