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Congenital rubella syndrome. Congenital rubella syndrome (CRS) occurs when an unborn baby is infected with the rubella virus (German measles) via maternal-fetal transmission and develops birth defects. [1] The most common congenital defects affect the ophthalmologic, cardiac, auditory, and neurologic systems. [2]
Rubella is a common infection in many areas of the world. Each year about 100,000 cases of congenital rubella syndrome occur. Rates of disease have decreased in many areas as a result of vaccination. There are ongoing efforts to eliminate the disease globally.
Feb 21, 2024 · Congenital rubella syndrome (CRS) happens when a pregnant person becomes infected with rubella (German measles) and passes it on to the fetus. “Congenital” means “present at birth.”. CRS causes a variety of issues during fetal development. These issues can affect your baby after birth, for example, causing cataracts or congenital heart ...
Aug 8, 2023 · Rubella, also known as German Measles, is a viral illness characterized by maculopapular rash, lymphadenopathy, and fever. It is a highly contagious but generally mild disease, without consequences in most cases. However, maternal infection during the first trimester of pregnancy can cause a fetal malformation syndrome called congenital rubella syndrome.
- Samarth Shukla, Nizar F. Maraqa
- 2023/08/08
The 1962–1965 rubella epidemic was an outbreak of rubella across Europe and the United States. [1] [2] The Rubella virus, also known as the German measles, is a single-stranded RNA virus from the family Togaviridae and genus Rubivirus. [3] Typically, the virus is transmitted via droplets, such as coughing or sneezing, however, congenital ...
May 15, 2024 · When a pregnant woman is infected with rubella in early pregnancy, she has up to a 90% chance of giving birth to a baby with CRS: CRS can cause hearing impairment, cataracts or glaucoma, heart defects, or developmental delays. 33% of infants born with CRS die before their first birthday. In 2019, an estimated 32,000 children were born with CRS.
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Congenital rubella syndrome is associated with congenital nuclear cataracts characterized by their ‘pearly white’ appearance. [9] This occurs due to the rubella virus slowing the proliferation and mitosis of epithelial cells in the lens. [8] As a result, lens fibers degenerate and become opaque, forming the cataract.
