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Nov 24, 2020 · The pathogenesis of dengue virus infection is attributed to complex interplay between virus, host genes and host immune response. Host factors such as antibody-dependent enhancement (ADE), memory cross-reactive T cells, anti-DENV NS1 antibodies, autoimmunity as well as genetic factors are major determinants of disease susceptibility.
May 1, 2024 · Many mechanisms contribute to liver dysfunction, including prolonged shock that causes hypoxic damage, direct liver cell death due to infection with the virus, and immune-mediated effects. Bleeding following dengue virus infection occurs due to multiple mechanisms including platelet activation by NS1, serotonin, and PAF, accompanied by a wide ...
Dec 7, 2023 · The weakness of current DHF risk maps Host serological profile and virus genetic diversity. Dengue is caused by four distinct serotypes of the dengue virus (DENV-1, DENV-2, DENV-3, and DENV-4) . Once a person is infected with one serotype, they develop lifelong immunity to that specific serotype but remain susceptible to the other serotypes.
Aug 16, 2018 · Purpose of Review: We aim to highlight the common infectious pathogens that affect evacuees, non-evacuees, and medical responders following hurricanes in the USA, in order to help clinicians quickly diagnose and treat patients and increase medical preparedness in hurricane affected areas. Recent Findings: Hurricanes facilitate the spread of infectious pathogens through population displacement ...
- Mihir A. Shukla, Laila Woc-Colburn
- 2018
Dengue hemorrhagic fever (DHF) is characterized by a fever that lasts from 2 to 7 days, with general signs and symptoms that could occur with many other illnesses (e.g., nausea, vomiting, abdominal pain, and headache). This stage is followed by the tendency to bruise easily or other types of skin hemorrhages, bleeding nose or gums, and possibly ...
Dec 15, 2021 · About 50 to 100 million people are newly infected annually, with almost 2.5 billion people living at risk and resulting in 20,000 deaths. Dengue virus infection is especially transmitted through bites of Aedes mosquitos, hugely spread in tropical and subtropical environments, mostly found in urban and semiurban areas. Unfortunately, there is no ...
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Dengue is an acute viral illness caused by RNA virus of the family Flaviviridae and spread by Aedes mosquitoes. Presenting features may range from asymptomatic fever to dreaded complications such as hemorrhagic fever and shock. A cute-onset high fever, muscle and joint pain, myalgia, cutaneous rash, hemorrhagic episodes, and circulatory shock ...
