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  1. Mar 14, 2024 · Environmental suitability for dengue transmission is expanding due to climate change, urbanisation and international travel 3. It is predicted that 2.25 (1.27–2.80) billion more people will be ...

    • J. Clarke
  2. May 4, 2018 · This process is achieved by inserting weekly district-level prospective data of outbreak cases and alarm indicators (see example in Fig 2 ). In these excel spreadsheets, displayed parameters (top-left hand corner) and the graph can guide the interpretation of the “alarm signal” field.

    • Laith Hussain-Alkhateeb, Axel Kroeger, Piero Olliaro, Joacim Rocklöv, Joacim Rocklöv, Maquins Odhiam...
    • 10.1371/journal.pone.0196811
    • 2018
    • PLoS One. 2018; 13(5): e0196811.
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  4. The OpenDengue dataset contains reported total case counts with each row corresponds to a unique location and time. Where reported, we include dengue cases at all levels of severity (dengue, dengue with/without warning signs, severe dengue, dengue haemorhaggic fever, dengue shock syndrome, dengue deaths) and methods of confirmation (suspected ...

  5. Dec 15, 2021 · Potential antiviral mechanism and molecular targets of the bioactive compounds inhibiting viral entry and replication of dengue virus. Infection of virus involves various stages: In the initial steps, DENV binds to cell receptors including mannose-binding receptor (MR) and DC-SIGN (dendritic cell-specific ICAM3 grabbing nonintegrin) receptor ...

    • 10.1155/2021/4224816
    • 2021
    • Biomed Res Int. 2021; 2021: 4224816.
  6. Nov 24, 2020 · Dengue virus genome encodes for three structural proteins (C, prM (M), and E) and seven non-structural (NS) proteins (NS1, NS2a, NS2B, NS3, NS4a, NS4B, and NS5). The most important non-structural protein which has been implicated in the pathogenesis of dengue viral infections is NS1 .

    • Puneet Bhatt, Sasidharan Pillai Sabeena, Muralidhar Varma, Govindakarnavar Arunkumar, Govindakarnava...
    • 10.1007/s00284-020-02284-w
    • 2021
    • Curr Microbiol. 2021; 78(1): 17-32.
  7. Apr 22, 2024 · Dengue viruses (DENV) are positive-stranded RNA viruses belonging to the Flaviviridae family. DENV is the causative agent of dengue, the most rapidly spreading viral disease transmitted by mosquitoes. Each year, millions of people contract the virus through bites from infected female mosquitoes of the Aedes species. In the majority of individuals, the infection is asymptomatic, and the immune ...

  8. Oct 1, 2023 · Different factors and mechanisms are thought to be involved in the presentation of DHF and DSS, including antibody-dependent enhancement, immune dysregulation, viral virulence, host genetic susceptibility, and preexisting dengue antibodies.

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