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2. www.nature.com › articles › s41597/024/03120-7A global dataset of publicly available dengue case count data

   www.nature.com › articles › s41597/024/03120-7

   Mar 14, 2024 · This new dataset can be used to better understand the long-term drivers of dengue transmission, improve estimates of disease burden, targeting and evaluation of interventions and improving...

   • Author: J. Clarke

3. opendengue.org › dataOpenDengue: Data

   opendengue.org › data

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   The OpenDengue project aims to build and maintain a database of dengue case counts for every dengue-affected country worldwide since 1990 or earlier. We collate data from a range of publicly available sources including ministry of health websites, peer-reviewed publications and other disease databases.

4. www.ncbi.nlm.nih.gov › pmc › articlesProduction, Transmission, Pathogenesis, and Control of Dengue ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Dec 15, 2021 · Potential antiviral mechanism and molecular targets of the bioactive compounds inhibiting viral entry and replication of dengue virus. Infection of virus involves various stages: In the initial steps, DENV binds to cell receptors including mannose-binding receptor (MR) and DC-SIGN (dendritic cell-specific ICAM3 grabbing nonintegrin) receptor ...

   • DOI: 10.1155/2021/4224816
   • Published: 2021

   • Publication: Biomed Res Int. 2021; 2021: 4224816.

5. www.ncbi.nlm.nih.gov › pmc › articlesCurrent Understanding of the Pathogenesis of Dengue Virus ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Nov 24, 2020 · The present article reviews the current concepts of the various mechanisms involved in the pathogenesis of dengue virus infection and gives a comprehensive overview of the multiple factors responsible for severe clinical manifestations of the disease.

   • Author: Puneet Bhatt, Sasidharan Pillai Sabeena, Muralidhar Varma, Govindakarnavar Arunkumar, Govindakarnava...
   • DOI: 10.1007/s00284-020-02284-w

   • Publish Year: 2021
   • Publication: Curr Microbiol. 2021; 78(1): 17-32.

6. jbiomedsci.biomedcentral.com › articles › 10Dengue virus pathogenesis and host molecular machineries

   jbiomedsci.biomedcentral.com › articles › 10

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   Apr 22, 2024 · Dengue virus infection is known to induce endoplasmic reticulum (ER) stress, triggering signaling pathways associated with ER stress during viral infections. These pathways activate genes that support cell survival and anti-viral defenses.

   • Author: Saumya Sinha

7. www.sciencedirect.com › science › articleDengue overview: An updated systemic review - ScienceDirect

   www.sciencedirect.com › science › article

   Oct 1, 2023 · Dengue is caused by the dengue virus (DENVs) infection and clinical manifestations include dengue fever (DF), dengue hemorrhagic fever (DHF), or dengue shock syndrome (DSS). Due to a lack of antiviral drugs and effective vaccines, several therapeutic and control strategies have been proposed.

8. People also ask

   How does a dengue virus interact with the host cellular machinery?

   • During dengue infection, the virus interacts with the host cellular machinery responsible for 5’ capping. DENV employs multiple strategies to hijack and manipulate this process. For instance, the virus sequesters essential host factors involved in capping, such as the cap-binding complex and associated enzymes.

   Dengue virus pathogenesis and host molecular machineries

   jbiomedsci.biomedcentral.com/articles/10.1186/s12929-024-01030-9

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   What factors are involved in the pathogenesis of dengue virus infection?

   • 1. Summary of various factors implicated in pathogenesis of dengue virus infection Higher viremia levels of DENV-2 and DENV-3 in secondary infections. Inhibits antiviral genes and enhancing the production of IL-10. Apart from various viral factors implicated in the pathogenesis of DENV infection, host genetic factors also play an important role.

   Current Understanding of the Pathogenesis of Dengue Virus Infection

   www.ncbi.nlm.nih.gov/pmc/articles/PMC7815537/

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   What causes severe manifestations of dengue virus disease?

   • The exact mechanisms responsible for severe manifestations of dengue virus disease are not yet fully elucidated and are likely to be multifactorial. DENV infection can have diverse presentations in different hosts, which cannot be explained by a single hypothesis alone.

   Current Understanding of the Pathogenesis of Dengue Virus Infection

   www.ncbi.nlm.nih.gov/pmc/articles/PMC7815537/

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9. www.nature.com › articles › s41577/019/0123-xAdaptive immune responses to primary and secondary dengue ...

   www.nature.com › articles › s41577/019/0123-x

   Jan 24, 2019 · Dengue is a viral illness that is spread primarily by Aedes mosquitoes and infects ~390 million people each year worldwide 1. It is caused by dengue virus (DENV), which belongs to the...