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2. jbiomedsci.biomedcentral.com › articles › 10Dengue virus pathogenesis and host molecular machineries

   jbiomedsci.biomedcentral.com › articles › 10

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   Apr 22, 2024 · Dengue viruses (DENV) are positive-stranded RNA viruses belonging to the Flaviviridae family. DENV is the causative agent of dengue, the most rapidly spreading viral disease transmitted by mosquitoes. Each year, millions of people contract the virus through bites from infected female mosquitoes of the Aedes species. In the majority of individuals, the infection is asymptomatic, and the immune ...

3. www.ncbi.nlm.nih.gov › pmc › articlesProduction, Transmission, Pathogenesis, and Control of Dengue ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Dec 15, 2021 · Naringenin (citrus flavanone) was evaluated against dengue viruses (serotypes 1–4) in Huh7.5 cells which impaired virus replication in human cells with IC 50 = 35.81, 17.97, 117.1, and 177.5 μM, respectively . Annona muricata aqueous leave extract was evaluated against dengue

   • DOI: 10.1155/2021/4224816
   • Published: 2021

   • Publication: Biomed Res Int. 2021; 2021: 4224816.

4. www.ncbi.nlm.nih.gov › pmc › articlesCurrent Understanding of the Pathogenesis of Dengue Virus ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Nov 24, 2020 · There are four serotypes of dengue virus which are antigenically distinct namely DENV-1, DENV-2, DENV-3, and DENV-4 . A fifth serotype (DENV-5) has been detected using isolation and genetic sequence analysis in Sarawak state of Malaysia in October 2013 . The incubation period of dengue virus infection is 4–7 days.

   • Author: Puneet Bhatt, Sasidharan Pillai Sabeena, Muralidhar Varma, Govindakarnavar Arunkumar, Govindakarnava...
   • DOI: 10.1007/s00284-020-02284-w

   • Publish Year: 2021
   • Publication: Curr Microbiol. 2021; 78(1): 17-32.

5. cdnsciencepub.com › doi › fullDengue virus: epidemiology, biology, and disease aetiology

   cdnsciencepub.com › doi › full

   Sep 3, 2021 · Dengue is a vector-borne viral disease caused by the flavivirus dengue virus (DENV). Approximately 400 million cases and 22 000 deaths occur due to dengue worldwide each year. It has been reported in more than 100 countries in tropical and subtropical regions. A positive-stranded enveloped RNA virus (DENV) is principally transmitted by Aedes mosquitoes. It has four antigenically distinct ...

   • Author: Sudipta Kumar Roy, Soumen Bhattacharjee

   • Publish Year: 2021

6. www.nejm.org › doi › fullDengue | New England Journal of Medicine

   www.nejm.org › doi › full

   Apr 12, 2012 · DOI: 10.1056/NEJMra1110265. VOL. 366 NO. 15. Dengue is a self-limited, systemic viral infection transmitted between humans by mosquitoes. The rapidly expanding global footprint of dengue is a ...

7. People also ask

   How does a dengue virus interact with the host cellular machinery?

   • During dengue infection, the virus interacts with the host cellular machinery responsible for 5’ capping. DENV employs multiple strategies to hijack and manipulate this process. For instance, the virus sequesters essential host factors involved in capping, such as the cap-binding complex and associated enzymes.

   Dengue virus pathogenesis and host molecular machineries

   jbiomedsci.biomedcentral.com/articles/10.1186/s12929-024-01030-9

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   What factors are involved in the pathogenesis of dengue virus infection?

   • 1. Summary of various factors implicated in pathogenesis of dengue virus infection Higher viremia levels of DENV-2 and DENV-3 in secondary infections. Inhibits antiviral genes and enhancing the production of IL-10. Apart from various viral factors implicated in the pathogenesis of DENV infection, host genetic factors also play an important role.

   Current Understanding of the Pathogenesis of Dengue Virus Infection

   www.ncbi.nlm.nih.gov/pmc/articles/PMC7815537/

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   What causes severe manifestations of dengue virus disease?

   • The exact mechanisms responsible for severe manifestations of dengue virus disease are not yet fully elucidated and are likely to be multifactorial. DENV infection can have diverse presentations in different hosts, which cannot be explained by a single hypothesis alone.

   Current Understanding of the Pathogenesis of Dengue Virus Infection

   www.ncbi.nlm.nih.gov/pmc/articles/PMC7815537/

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8. www.nature.com › articles › s41467/019/09391-8Structure mapping of dengue and Zika viruses reveals ...

   www.nature.com › articles › s41467/019/09391-8

   Mar 29, 2019 · The viruses were then separated into three reactions: (1) we added 1:20 the volume of 1M NAI (03-310, Merck, 25 µl of NAI in 500 µl of virus in cell media) and incubated the reaction for 15 min ...

9. www.sciencedirect.com › science › articleDengue virus infection – a review of pathogenesis, vaccines ...

   www.sciencedirect.com › science › article

   Jan 15, 2023 · FcR-dependent ADE is the most common mechanism for a wide range of virus infection such as HIV, influenza A, dengue and Ebola. Cells which have FcR such as monocytes, B cells, neutrophils and macrophages are easily attached by the virus-antibody complexes because the Fc region of the antibody will bind on the cell surface with FcR which leads ...