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  2. Nov 24, 2020 · The present article reviews the current concepts of the various mechanisms involved in the pathogenesis of dengue virus infection and gives a comprehensive overview of the multiple factors responsible for severe clinical manifestations of the disease.

  3. Apr 23, 2024 · Most people who get dengue will not have symptoms. But for those who do, the most common symptoms are high fever, headache, body aches, nausea, and rash. Most will get better in 1–2 weeks. Some people develop severe dengue and need care in a hospital. In severe cases, dengue can be fatal.

  4. Oct 5, 2022 · When symptoms do occur, they may be mistaken for other illnesses — such as the flu — and usually begin four to 10 days after you are bitten by an infected mosquito. Dengue fever causes a high fever — 104 F (40 C) — and any of the following signs and symptoms: Headache. Muscle, bone or joint pain.

  5. Aug 14, 2023 · Careful epidemiologic and experimental challenge studies in humans have provided valuable information on DENV infection, but detailed data on virus distribution in vivo are available only from small numbers of patients with more severe disease, unusual manifestations, or the later stages of infection.

  6. Apr 12, 2012 · Although most dengue virus infections are asymptomatic, a wide variety of clinical manifestations may occur, ranging from mild febrile illness to severe and fatal disease. 1 The...

  7. May 18, 2022 · Dengue fever is an infectious disease carried by mosquitoes and caused by any of four related dengue viruses. This disease used to be called "break-bone" fever because it sometimes causes severe joint and muscle pain that feels like bones are breaking.

  8. The dengue virus is spread through a human-to-mosquito-to-human cycle of transmission, with the mosquito Aedes aegypti as the primary vector. These mosquitoes live near humans in...

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